Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 18/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759190 | 0.90 | AR (0.74) | ARHDAC1 | |
| SCHEMBL8939551 | 0.90 | AR (0.74) | ARHDAC1 | |
| SCHEMBL7759696 | 0.89 | AR (0.67) | ARPGR | |
| SCHEMBL7756025 | 0.87 | AR (0.60) | ARHDAC1PGR | |
| SCHEMBL7759173 | 0.84 | AR (0.63) | ARHDAC1 | |
| SCHEMBL30291858 | 0.84 | AR (1.00) | ARHDAC1 | |
| SCHEMBL1435262 | 0.84 | AR (1.00) | ARHDAC1 | |
| SCHEMBL8939558 | 0.83 | AR (0.77) | ARHDAC1PGR | |
| SCHEMBL8177485 | 0.81 | AR (0.59) | ARPGR | |
| SCHEMBL30291848 | 0.81 | AR (0.77) | ARHDAC1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738263-B1 | SUBSTITUTED PHENYLIMIDAZOLIDINES HAVING ANTIANDROGEN ACTIVITY | AVENTIS PHARMA SA (FR) | 2001-04-04 | — | — | EP | disclosed |
| US-5750553-A | ANTIANDROGENIC AGENTS | ROUSSEL UCLAF (FR) | 1998-05-12 | — | — | US | disclosed |