SCHEMBL7760665

SCHEMBL7760665

CCCC(C)(C)COCC(C)(C)CCC

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27826077 0.94 LMNA (0.32) LMNAHSD17B10TSHRMAPK1
SCHEMBL13953855 0.92 LMNA (0.31) LMNAHSD17B10
SCHEMBL10147430 0.88 LMNA (0.32) LMNAHSD17B10TSHRMAPK1
SCHEMBL27797477 0.86 HSD17B10 (0.32) LMNAHSD17B10
SCHEMBL2099613 0.84 LMNA (0.34) LMNAHSD17B10
SCHEMBL21311740 0.83
SCHEMBL9451864 0.82 TSHR (0.32) LMNATSHRMAPK1
SCHEMBL27905237 0.82 CYP3A4 (0.31) HSD17B10TSHR
SCHEMBL27888438 0.82 CYP3A4 (0.31) HSD17B10TSHR
SCHEMBL27826133 0.82 TSHR (0.41) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8344089-B2 Branched polydimethylsiloxane-polyoxyalkylene copolymers, a process for preparing them and their use as anti-misting additives in UV-curing silicones EVONIK GOLDSCHMIDT GMBH (DE) 2013-01-01 US disclosed
CN-102043339-A Positive radiation-sensitive resin composition, and interlayer insulating film and method for forming the same JSR CORP 2011-05-04 CN disclosed
US-20100298485-A1 BRANCHED POLYDIMETHYLSILOXANE-POLYOXYALKYLENE COPOLYMERS, A PROCESS FOR PREPARING THEM AND THEIR USE AS ANTI-MISTING ADDITIVES IN UV-CURING SILICONES EVONIK GOLDSCHMIDT GMBH (DE) 2010-11-25 US disclosed
US-7825205-B2 Process for the preparation of SiOC-linked, linear polydimethylsiloxane-polyoxyalkylene block copolymers and their use EVONIK GOLDSCHMIDT GMBH (DE) 2010-11-02 US disclosed
US-7825206-B2 Process for reacting polyorganosiloxanes and their use EVONIK GOLDSCHMIDT GMBH (DE) 2010-11-02 US disclosed
US-7442666-B2 Catalytic system for the dehydrogenative condensation of polyorganosiloxanes with alcohols and a process for preparing organically modified polyorganosiloxanes GOLDSCHMIDT GMBH (DE) 2008-10-28 US disclosed
US-20080153992-A1 Process for the preparation of SiOC-linked, linear polydimethylsiloxane-polyoxyalkylene block copolymers and their use EVONIK GOLDSCHMIDT GMBH (DE) 2008-06-26 US disclosed
US-20080153934-A1 Process for reacting polyorganosiloxanes and their use EVONIK GOLDSCHMIDT GMBH (DE) 2008-06-26 US disclosed
US-20070299231-A1 POLYSILOXANES CONTAINING (METH)ACRYLIC ESTER GROUPS ATTACHED VIA SiOC GROUPS, PROCESSES FOR PREPARING THEM AND THEIR USE AS A RADIATION-CURABLE ADHESIVE COATING GOLDSCHMIDT GMBH (DE) 2007-12-27 US disclosed
EP-0734429-B1 USE OF TERTIARY-HEXYL METHYL ETHER AS A MOTOR GASOLINE ADDITIVE EXXON CHEMICAL PATENTS INC (US) 2001-04-18 EP disclosed
EP-0734429-A1 USE OF TERTIARY-HEXYL METHYL ETHER AS A MOTOR GASOLINE ADDITIVE EXXON CHEMICAL PATENTS INC. (US) 1996-10-02 EP disclosed
EP-0646103-A4 BF 3?-TERTIARY ETHERATE COMPLEXES FOR ISOBUTYLENE POLYMERIZATION. AMOCO CORP (US) 1995-08-09 EP disclosed
WO-1995016763-A1 USE OF TERTIARY-HEXYL METHYL ETHER AS A MOTOR GASOLINE ADDITIVE EXXON CHEMICAL PATENTS INC. (US) 1995-06-22 WO disclosed
EP-0646103-A1 BF 3?-TERTIARY ETHERATE COMPLEXES FOR ISOBUTYLENE POLYMERIZATION. AMOCO CORP (US) 1995-04-05 EP disclosed
US-5177290-A Tert-Alkyl Ether, Bifunctional Catalyst, Monofunctional Acid Catalyst EXXON CHEMICAL PATENTS INC. (US) 1993-01-05 US disclosed
WO-1992012111-A1 ISOPRENE PROCESS AND CATALYSTS THEREFOR EXXON CHEMICAL PATENTS INC. (US) 1992-07-23 WO disclosed
EP-0284005-B1 METHOD OF PRODUCTION OF POLYOLEFINS IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-12-18 EP disclosed
US-4981930-A POLYMERIZATION CATALYSTS IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) 1991-01-01 US disclosed
EP-0284005-A2 Method of production of polyolefins IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-09-28 EP disclosed
EP-0050869-A1 Process for the manufacture of N-tert.-alkylamines or cycloalkylamines and formic acid esters Degussa Aktiengesellschaft (DE) 1982-05-05 EP disclosed