Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL7764866 | 0.96 | S1PR2 (0.41) | FFAR4FFAR1PPARGPPARAMEN1 | |
| Malonic Acid SCHEMBL7764459 | 0.91 | CNR2 (0.43) | PPARGPPARAMEN1KMT2A | |
| Acetic Acid SCHEMBL7764388 | 0.91 | CNR2 (0.42) | PPARGPPARAALDH1A1MEN1KMT2A | |
| Adipic Acid SCHEMBL7764425 | 0.89 | FFAR4 (0.51) | FFAR4FFAR1GPR84PPARGPPARD | |
| Lactic Acid SCHEMBL7768064 | 0.88 | CSNK1E (0.41) | FFAR1GPR84PPARGPPARAALDH1A1 | |
| Cadaverine Tartrate SCHEMBL7764905 | 0.87 | CSNK1E (0.40) | FFAR1GPR84PPARGPPARAALDH1A1 | |
| Hydrochloric Acid SCHEMBL7766063 | 0.86 | GRIN2D (0.43) | — | |
| Hydrochloric Acid SCHEMBL8722907 | 0.86 | GRIN2D (0.43) | — | |
| Hydrochloric Acid SCHEMBL7760756 | 0.86 | GRIN2D (0.43) | — | |
| Succinic Acid SCHEMBL7768273 | 0.85 | S1PR1 (0.48) | FFAR4FFAR1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825175-B1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0825175-A1 | Quaternary ammonium disinfectant | NICCA CHEMICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |