Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tectorigenin SCHEMBL29353966 | 0.86 | EGFR (1.00) | EGFRALDH1A1CYP3A4MAPTHPGD | |
| Tectorigenin SCHEMBL351641 | 0.86 | EGFR (1.00) | EGFRALDH1A1CYP3A4MAPTHPGD | |
| Irilin D SCHEMBL571722 | 0.85 | EGFR (0.80) | EGFRALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL12777134 | 0.85 | EGFR (0.74) | EGFRALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL29145266 | 0.84 | EGFR (0.70) | EGFRALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL12777120 | 0.83 | EGFR (0.76) | EGFRALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL29887713 | 0.83 | EGFR (0.76) | EGFRALDH1A1CYP3A4MAPTHPGD | |
| Iristectorigenin A SCHEMBL6337637 | 0.83 | EGFR (0.76) | EGFRALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL30708523 | 0.83 | EGFR (0.76) | EGFRALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL14513481 | 0.83 | EGFR (0.76) | EGFRALDH1A1CYP3A4MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1096929-A1 | THERAPEUTIC COMPOSITION BASED ON FLAVONOIDS FOR USE IN THE TREATMENT OF TUMOURS WITH CYTOTOXIC AGENTS | LABORATOIRE L. LAFON (FR) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003707-A1 | THERAPEUTIC COMPOSITION BASED ON FLAVONOIDS FOR USE IN THE TREATMENT OF TUMOURS WITH CYTOTOXIC AGENTS | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |