Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 1.00 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.62 |
| ▸ | RELA | Q04206 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tectorigenin SCHEMBL29353966 | 1.00 | EGFR (1.00) | EGFRALDH2POLBKDM4EMEN1 | |
| Irisolidone SCHEMBL30997344 | 0.91 | EGFR (0.84) | EGFRALDH2POLBKDM4EMEN1 | |
| Irisolidone SCHEMBL1974327 | 0.91 | EGFR (0.84) | EGFRALDH2POLBKDM4EMEN1 | |
| Tectorigenin SCHEMBL2074313 | 0.89 | EGFR (0.80) | EGFRALDH2POLBKDM4EMEN1 | |
| Irilin D SCHEMBL571722 | 0.89 | EGFR (0.80) | EGFRALDH2POLBKDM4EMEN1 | |
| SCHEMBL14513481 | 0.86 | EGFR (0.76) | EGFRALDH2POLBKDM4EMEN1 | |
| SCHEMBL12777120 | 0.86 | EGFR (0.76) | EGFRALDH2POLBKDM4EMEN1 | |
| Iristectorigenin A SCHEMBL6337637 | 0.86 | EGFR (0.76) | EGFRALDH2POLBKDM4EMEN1 | |
| SCHEMBL7760758 | 0.86 | EGFR (0.76) | EGFRALDH2POLBKDM4EMEN1 | |
| SCHEMBL30708523 | 0.86 | EGFR (0.76) | EGFRALDH2POLBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12521366-B2 | Anti-obesity composition and composition for oral administration | TOYO SHINYAKU CO., LTD. (JP) | 2026-01-13 | — | — | US | claimed |
| CN-120078850-A | Sargentodoxa cuneata-herba patriniae extract, and pharmaceutical composition and application thereof | 扬州大学 | 2025-06-03 | — | — | CN | claimed |
| CN-120064510-A | Method for checking medicine for treating hearing loss | 河北永丰药业有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-116672353-B | Traditional Chinese medicine composition for enhancing phagocytic capacity of macrophages and preparation method thereof | 浙江大学智能创新药物研究院 | 2025-05-16 | — | — | CN | claimed |
| CN-119909108-A | Nanoparticle compound for treating ulcerative colitis and preparation method and application thereof | 广州医科大学附属第一医院（广州呼吸中心） | 2025-05-02 | — | — | CN | claimed |
| CN-116725017-B | Application of tectorigenin and blackberry lily glycoside in crop weed and pest control | 武汉大学 | 2025-04-25 | — | — | CN | claimed |
| CN-119823936-A | Kudzuvine flower-derived extracellular vesicle-like particles, and preparation method and application thereof | 广州中医药大学第三附属医院(广州中医药大学第三临床医学院、广州中医药大学附属骨伤科医院、广东省中医骨伤研究院) | 2025-04-15 | — | — | CN | claimed |
| CN-118584013-B | Method for simultaneously determining contents of various components in turbidity-resolving, stagnation-resolving and arthralgia-removing formula based on UHPLC-QqQ-MS/MS technology | 福建中医药大学 | 2025-04-08 | — | — | CN | claimed |
| CN-118496341-B | Iris polypeptide product and application thereof | 上海肠寿医学科技有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119504684-A | Method for extracting tectorigenin from flos puerariae lobatae and application thereof | 武汉润福令科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| WO-2003015767-A2 | USE OF TECTORIGENIN FOR THE PRODUCTION OF COSMETIC OR DERMATOLOGICAL PREPARATIONS FOR THE PROPHYLAXIS AND TREATMENT OF INFLAMMATORY SKIN CONDITIONS AND/OR FOR SKIN PROTECTION OF DETERMINATE SENSITIVE AND DRY SKIN | BEIERSDORF AG (DE) | 2003-02-27 | — | — | WO | claimed |
| EP-1064009-B9 | UTILIZATION OF EXTRACTS FROM IRIS PLANTS, CIMICIFUGA RACEMOSA AND TECTORIGENIN AS AN ESTROGEN-LIKE ORGAN-SELECTIVE MEDICAMENT WITHOUT UTEROTROPIC EFFECTS | BIONORICA AG (DE) | 2003-02-05 | — | — | EP | claimed |
| WO-2002102349-A1 | COMPOSITIONS FOR PREVENTION AND TREATMENT OF SKIN WRINKLE | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2002-12-27 | — | — | WO | claimed |
| WO-2002092111-A1 | USE OF EXTRACTS AND PREPARATIONS FROM IRIS PLANTS AND TECTORIGENIN AS MEDICAMENTS | BIONORICA AG (DE) | 2002-11-21 | — | — | WO | claimed |
| EP-1064009-B1 | UTILIZATION OF EXTRACTS FROM IRIS PLANTS, CIMICIFUGA RACEMOSA AND TECTORIGENIN AS AN ESTROGEN-LIKE ORGAN-SELECTIVE MEDICAMENT WITHOUT UTEROTROPIC EFFECTS | BIONORICA AG (DE) | 2002-10-02 | — | — | EP | claimed |
| US-20020107282-A1 | Cosmetic composition containing an aminophenol derivative and an isoflavonoid | L'OREAL (FR) | 2002-08-08 | — | — | US | claimed |
| CN-1352935-A | Cosmetics composition containing aminophenol derivatives and isoflavone like substance | OREAL (FR) | 2002-06-12 | — | — | CN | claimed |
| CN-1293575-A | Use of extracts of Iridaceae and Cimicifuga racemosa and tectorigenin as estrogen-type organ-selective medicament without uterotrophic effect | BAIAONORICA PHARMACEUTICAL GMB (DE) | 2001-05-02 | — | — | CN | claimed |
| EP-1064009-A1 | UTILIZATION OF EXTRACTS FROM IRIS PLANTS, CIMICIFUGA RACEMOSA AND TECTORIGENIN AS AN ESTROGEN-LIKE ORGAN-SELECTIVE MEDICAMENT WITHOUT UTEROTROPIC EFFECTS | Bionorica AG (DE) | 2001-01-03 | — | — | EP | claimed |
| WO-1999047149-A1 | UTILIZATION OF EXTRACTS FROM IRIS PLANTS, CIMICIFUGA RACEMOSA AND TECTORIGENIN AS AN ESTROGEN-LIKE ORGAN-SELECTIVE MEDICAMENT WITHOUT UTEROTROPIC EFFECTS | BIONORICA ARZNEIMITTEL GMBH (DE) | 1999-09-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107282-A1 | Cosmetic composition containing an aminophenol derivative and an isoflavonoid | TYR, CYP19A1, EYA3 | EGFR 1685/4885ALDH2 2429/4885POLB 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.