Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | HRH1 | P35367 | 2/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12197971 | 0.93 | TDP1 (0.62) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| Bicarbonate SCHEMBL9520631 | 0.92 | TBXAS1 (0.64) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| Bromide SCHEMBL18838899 | 0.91 | TDP1 (0.61) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| SCHEMBL1741942 | 0.87 | TDP1 (0.60) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| SCHEMBL7544154 | 0.87 | TDP1 (0.56) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| SCHEMBL104468 | 0.85 | CHRNA7 (0.57) | TDP1L3MBTL1HRH1CYP2A6CHRNA7 | |
| Hydrochloric Acid SCHEMBL1740801 | 0.85 | TDP1 (0.58) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| SCHEMBL29485634 | 0.85 | HRH1 (0.81) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| SCHEMBL8658187 | 0.85 | HRH1 (0.81) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| SCHEMBL2845851 | 0.85 | HRH1 (0.81) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085853-A1 | HETEROCYCLIC ESTER AND AMIDE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL Holdings, Inc. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999062487-A1 | HETEROCYCLIC ESTER AND AMIDE HAIR GROWTH COMPOSITIONS AND USES | GPI NIL HOLDINGS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| US-5990131-A | OF GIVEN FORMULA WHICH HAVE A HIGH AFFINITY FOR FKBPS (FK506 BINDING PROTEINS, A CLASS OF IMMUNOPHILINS) ARE POTENT ROTAMASE INHIBITORS AND EXHIBIT EXCELLENT NEUROTROPHIC EFFECTS; NO IMMUNOSUPPRESSIVE ACTIVITY | GPI NIL HOLDINGS INC. (US) | 1999-11-23 | — | — | US | disclosed |