Styrene

Styrene

SCHEMBL7761168

C/C=C(\C)C(=O)O.C=C(CCCC)C(=O)O.C=Cc1ccccc1.CCCC/C=C(\C)C(=O)O

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.37
LMNA P02545 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
CES2 O00748 2/20 0.34
CES1 P23141 2/20 0.34
HDAC3 O15379 1/20 0.34
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
TBXAS1 P24557 1/20 0.33
ELANE P08246 1/20 0.32
EGFR P00533 1/20 0.32
GRIK1 P39086 1/20 0.32
PPARG P37231 2/20 0.31
PTGES O14684 1/20 0.31
ALOX5 P09917 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
SOAT2 O75908 1/20 0.31
SOAT1 P35610 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL10899832 0.94 AKR1C3 (0.38) AKR1C3LMNATDP1CES2CES1
Styrene SCHEMBL10596851 0.94 AKR1C3 (0.38) AKR1C3LMNATDP1CES2CES1
Styrene SCHEMBL7950541 0.93 AKR1C3 (0.37) AKR1C3LMNATDP1CES2CES1
Styrene SCHEMBL2042273 0.93 AKR1C3 (0.42) AKR1C3LMNATDP1CES2CES1
Styrene SCHEMBL8352287 0.93 AKR1C3 (0.42) AKR1C3LMNATDP1CES2CES1
Styrene SCHEMBL9272226 0.91 TDP1 (0.40) AKR1C3LMNATDP1CES2CES1
Styrene SCHEMBL18546160 0.90 AKR1C3 (0.41) AKR1C3LMNATDP1CES2CES1
Styrene SCHEMBL9785976 0.89 AKR1C3 (0.38) AKR1C3LMNATDP1CES2CES1
Styrene SCHEMBL3141180 0.89 AKR1C3 (0.46) AKR1C3LMNATDP1CES2CES1
Styrene SCHEMBL393960 0.89 AKR1C3 (0.46) AKR1C3LMNATDP1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0870549-B1 METALLIC SHEET HAVING RUST-PREVENTIVE ORGANIC COATING THEREON, PROCESS FOR THE PRODUCTION THEREOF AND TREATING FLUID THEREFOR NIPPON STEEL CORP (JP) 2001-03-21 EP disclosed
EP-0870549-A1 METALLIC SHEET HAVING RUST-PREVENTIVE ORGANIC COATING THEREON, PROCESS FOR THE PRODUCTION THEREOF AND TREATING FLUID THEREFOR NIPPON STEEL CORPORATION (JP) 1998-10-14 EP disclosed