Styrene

Styrene

SCHEMBL2042273

C=C(CCCC)C(=O)O.C=Cc1ccccc1.CC=C(C)C(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.42
LMNA P02545 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
HDAC3 O15379 2/20 0.38
ELANE P08246 1/20 0.36
EGFR P00533 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
GAA P10253 1/20 0.35
PTGES O14684 1/20 0.34
ALOX5 P09917 1/20 0.34
PPARG P37231 1/20 0.34
HTT P42858 1/20 0.34
MAPT P10636 1/20 0.34
KDM4E B2RXH2 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL18546160 0.97 AKR1C3 (0.41) AKR1C3LMNATDP1ALDH1A1TSHR
Styrene SCHEMBL7761168 0.93 AKR1C3 (0.37) AKR1C3LMNATDP1ALDH1A1TSHR
Styrene SCHEMBL258132 0.91 LMNA (0.47) AKR1C3LMNATDP1ALDH1A1TSHR
Styrene SCHEMBL5270544 0.91 LMNA (0.47) AKR1C3LMNATDP1ALDH1A1TSHR
Styrene SCHEMBL17065130 0.91 LMNA (0.47) AKR1C3LMNATDP1ALDH1A1TSHR
Styrene SCHEMBL3430407 0.90 LMNA (0.44) AKR1C3LMNATDP1ALDH1A1TSHR
Styrene SCHEMBL6342331 0.88 ALDH1A1 (0.36) AKR1C3LMNATDP1ALDH1A1TSHR
Styrene SCHEMBL7783115 0.87 LMNA (0.44) AKR1C3LMNATDP1ALDH1A1TSHR
Styrene SCHEMBL987788 0.87 LMNA (0.44) LMNATDP1ALDH1A1TSHRCES2
Styrene SCHEMBL4691116 0.87 AKR1C3 (0.46) AKR1C3TDP1ALDH1A1TSHRHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1646664-B2 METHOD FOR THE PRODUCTION OF POLYVINYL ALCOHOL-FREE, AQUEOUS POLYMER DISPERSIONS WACKER CHEMIE AG (DE) 2011-10-12 EP disclosed
EP-1608700-B1 USE OF POLYMERS FOR STARCH MODIFICATION WACKER CHEMIE AG (DE) 2011-06-29 EP disclosed
EP-1585775-B1 METHOD FOR PRODUCING SILICONE-TREATED POLYMERS WACKER CHEMIE AG (DE) 2008-07-02 EP disclosed
EP-1713844-B1 METHOD FOR PRODUCTION OF MIXED POLYMERS CONTAINING SILICON WACKER CHEMIE AG (DE) 2007-05-30 EP disclosed
EP-1646664-B1 METHOD FOR THE PRODUCTION OF POLYVINYL ALCOHOL-FREE, AQUEOUS POLYMER DISPERSIONS WACKER POLYMER SYSTEMS GMBH (DE) 2006-10-04 EP disclosed
EP-1203648-B1 Method for the fabrication of wooden fibreboards WACKER POLYMER SYSTEMS GMBH (DE) 2005-09-21 EP disclosed
EP-1136516-B1 Use of a cross-linkable polymer composition WACKER POLYMER SYSTEMS GMBH (DE) 2005-01-05 EP disclosed
EP-1336623-B1 Binder composition in powder form WACKER POLYMER SYSTEMS GMBH (DE) 2004-08-25 EP disclosed
EP-1342744-B1 Process for cold pressing composite materials WACKER POLYMER SYSTEMS GMBH (DE) 2004-01-21 EP disclosed
EP-1203647-B1 Method for the manufacturing of wooden fibreboards WACKER POLYMER SYSTEMS GMBH (DE) 2004-01-14 EP disclosed
US-20010025085-A1 Aromatic vinyl resin material and molded products thereof IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-09-27 US disclosed
EP-1134255-A2 Polymer composition for the flexibilisation of construction materials Wacker-Chemie GmbH (DE) 2001-09-19 EP disclosed
WO-2001057117-A1 SELF-REINFORCING THERMOPLASTICALLY-DEFORMABLE SEMI-FINISHED PRODUCT, IN PARTICULAR FOR THE PRODUCTION OF SANITARY ITEMS, METHOD FOR PRODUCTION THEREOF AND MOULDED BODIES MADE THEREFROM Röhm GmbH & Co. KG (DE) 2001-08-09 WO disclosed
EP-1117741-A1 THERMOPLASTIC MOULDING MATERIALS FOR INTERNAL APPLICATIONS IN A MOTOR VEHICLE BASF AKTIENGESELLSCHAFT (DE) 2001-07-25 EP disclosed
US-6207753-B1 RESIN MATERIALS FOR PRODUCING MOLDED PRODUCTS ENDOWED WITH EXCELLENT HEAT RESISTANCE, SOLVENT RESISTANCE, TOUGHNESS, TENSILE ELONGATION AND TRANSPARENCY IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-03-27 US disclosed
WO-2000044831-A1 MOULDING MATERIALS FOR USE IN MOTOR VEHICLE INTERIORS BASF AKTIENGESELLSCHAFT (DE) 2000-08-03 WO disclosed
WO-2000020500-A1 THERMOPLASTIC MOULDING MATERIALS FOR INTERNAL APPLICATIONS IN A MOTOR VEHICLE BASF AKTIENGESELLSCHAFT (DE) 2000-04-13 WO disclosed
EP-0973835-A1 SANITARY APPLIANCES WITH A CASING Röhm Gesellschaft mit beschränkter Haftung (DE) 2000-01-26 EP disclosed
EP-0911349-A1 Aromatic vinyl resin material and molded products thereof Idemitsu Petrochemical Co., Ltd. (JP) 1999-04-28 EP disclosed
WO-1998045375-A1 SANITARY APPLIANCES WITH A CASING RÖHM GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG (DE) 1998-10-15 WO disclosed