Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935980 | 0.94 | TDP1 (0.59) | TDP1MMP8SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7309709 | 0.89 | MMP8 (0.56) | TDP1MMP8SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL2427317 | 0.86 | MMP8 (0.54) | TDP1MMP8SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL29681728 | 0.85 | TDP1 (0.51) | TDP1MMP8SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL3067055 | 0.84 | MMP8 (0.52) | TDP1MMP8SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7058697 | 0.84 | MMP8 (0.52) | TDP1MMP8SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7059324 | 0.84 | SMN1; SMN2 (0.56) | TDP1MMP8SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL6714506 | 0.84 | TDP1 (0.65) | TDP1MMP8SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL28004307 | 0.84 | TDP1 (0.57) | TDP1MMP8SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL8702350 | 0.83 | MDM2 (0.51) | TDP1MMP8SMN1; SMN2L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079176-A1 | PROCESS FOR PREPARATION OF 3-[(1'-(ALKOXYCARBONYL)-3'-PHENYLPROPYL)AMINO]-2-OXO-[1]-BENZAZEPINE AND ITS DERIVATIVES | SCINOPHARM SINGAPORE PTE LTD (SG) | 2001-10-25 | — | — | WO | disclosed |