Dinotefuran

Dinotefuran

SCHEMBL7762050

CNC(=N[N+](=O)[O-])NC[C@@H]1CCOC1

nearest known ligand 0.64

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Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 14/20 0.34
GSK3B P49841 4/20 0.31
KCNH2 Q12809 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dinotefuran SCHEMBL26337 1.00 NAMPT (0.34) NAMPTGSK3BKCNH2
Dinotefuran SCHEMBL182310 1.00 NAMPT (0.34) NAMPTGSK3BKCNH2
Dinotefuran SCHEMBL29992195 1.00 NAMPT (0.34) NAMPTGSK3BKCNH2
Dinotefuran SCHEMBL28442208 1.00 NAMPT (0.34) NAMPTGSK3BKCNH2
Dinotefuran SCHEMBL237819 1.00 NAMPT (0.34) NAMPTGSK3BKCNH2
Dinotefuran SCHEMBL23070869 0.99 NAMPT (0.33) NAMPTGSK3BKCNH2
SCHEMBL2194777 0.91 NAMPT (0.34) NAMPTGSK3BKCNH2
Dinotefuran SCHEMBL30985200 0.91 NAMPT (0.32) NAMPTGSK3BKCNH2
Dinotefuran SCHEMBL19019789 0.87
Dinotefuran SCHEMBL19019790 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001031667-A NITROGUANIDINE DERIVATIVE CONTAINING OPTICALLY ACTIVE TETRAHYDROFURANYL GROUP, ITS PRODUCTION, AND INSECTICIDE CONTAINING THE SAME DERIVATIVE AS EFFECTIVE INGREDIENT MITSUI CHEMICALS INC 2001-02-06 JP disclosed