Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 14/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dinotefuran SCHEMBL237819 | 0.91 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL7762050 | 0.91 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL182310 | 0.91 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL26337 | 0.91 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL29992195 | 0.91 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL28442208 | 0.91 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL23070869 | 0.90 | NAMPT (0.33) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL30985200 | 0.88 | NAMPT (0.32) | NAMPTGSK3BKCNH2 | |
| SCHEMBL3255311 | 0.88 | GSK3B (0.31) | NAMPTGSK3BKCNH2 | |
| SCHEMBL13872447 | 0.88 | GSK3B (0.31) | NAMPTGSK3BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400552-A | A kind of synthesis preparation method of 2- nitro -1,3- bis- [(tetrahydro -3- furans) methyl] guanidine | 江苏中谱检测有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109400552-A | A kind of synthesis preparation method of 2- nitro -1,3- bis- [(tetrahydro -3- furans) methyl] guanidine | 江苏中谱检测有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109400552-A | A kind of synthesis preparation method of 2- nitro -1,3- bis- [(tetrahydro -3- furans) methyl] guanidine | 江苏中谱检测有限公司 | 2019-03-01 | — | — | CN | disclosed |
| EP-1985614-B1 | IMPROVED METHOD FOR PRODUCING NITROGUANIDINE DERIVATIVE | MITSUI CHEMICALS AGRO INC (JP) | 2013-09-25 | — | — | EP | disclosed |
| US-7977496-B2 | Process for producing nitroguanidine derivatives | MITSUI CHEMICALS, INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20090176990-A1 | PROCESS FOR PRODUCING NITROGUANIDINE DERIVATIVES | MITSUI CHEMICALS, INC. (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-1985614-A1 | IMPROVED METHOD FOR PRODUCING NITROGUANIDINE DERIVATIVE | Mitsui Chemicals, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176990-A1 | PROCESS FOR PRODUCING NITROGUANIDINE DERIVATIVES | NOS2, NOS1, NOS3 | NAMPT 2261/4885GSK3B 3886/4885KCNH2 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.