Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369898 | 1.00 | LMNA (0.79) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL4379656 | 1.00 | LMNA (0.79) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL4369351 | 1.00 | LMNA (0.79) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| Water SCHEMBL7764910 | 0.99 | LMNA (0.78) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL7225048 | 0.92 | LMNA (0.78) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL7227083 | 0.91 | LMNA (0.66) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL7227115 | 0.90 | LMNA (0.75) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL7236649 | 0.90 | LMNA (0.77) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL7225535 | 0.90 | LMNA (0.77) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL7226923 | 0.90 | LMNA (0.77) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001085728-A2 | ANTIBACTERIAL CHIRAL 8-(SUBSTITUTED PIPERIDINO)-BENZO [I, J] QUINOLIZINES, PROCESSES, COMPOSITIONS AND METHODS OF TREATMENT | WOCKHARDT LIMITED (IN) | 2001-11-15 | — | — | WO | disclosed |