Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20182831 | 0.79 | APLNR (0.33) | PTPN1APLNR | |
| SCHEMBL2479329 | 0.73 | FFAR3 (0.38) | EP300HIF1ACREBBP | |
| SCHEMBL15870316 | 0.72 | PRKD3 (0.44) | APP | |
| SCHEMBL789290 | 0.72 | PRKD3 (0.44) | APP | |
| SCHEMBL21751436 | 0.72 | PRKD3 (0.44) | APP | |
| SCHEMBL21771475 | 0.71 | CHRM2 (0.33) | EP300HIF1ACREBBP | |
| SCHEMBL18337481 | 0.70 | FFAR3 (0.35) | EP300HIF1ACREBBP | |
| SCHEMBL5826277 | 0.69 | PRKD3 (0.65) | PTPN1KDM4ENSD2ABL1POLB | |
| SCHEMBL17220932 | 0.69 | PRKD3 (0.65) | PTPN1KDM4ENSD2ABL1POLB | |
| Quinic Acid SCHEMBL3771151 | 0.68 | HSD17B10 (0.37) | PTPN1KDM4EAPLNRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1094825-A2 | PHARMACEUTICAL GRADE ST. JOHN'S WORT | Pharmaprint, Inc. (US) | 2001-05-02 | — | — | EP | disclosed |
| US-6113907-A | MEASUREMENT OF SAMPLE, BINDING AND DETERMINATION OF HYPERICIN CONCENTRATION FOR MUSCARINIC M1 RECEPTORS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2000-09-05 | — | — | US | disclosed |
| WO-1999021005-A2 | PHARMACEUTICAL GRADE ST. JOHN'S WORT | PHARMAPRINT, INC. (US) | 1999-04-29 | — | — | WO | disclosed |