Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.37 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | GGH | Q92820 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2248015 | 1.00 | KMT2A (0.44) | KMT2AALOX15BLMPMP22FOLH1 | |
| SCHEMBL27341927 | 0.87 | FOLH1 (0.52) | FOLH1NAALAD2RIMKLAGGH | |
| SCHEMBL1267740 | 0.86 | NOD1 (0.42) | KMT2AALOX15BLMPMP22FOLH1 | |
| SCHEMBL1226603 | 0.85 | KMT2A (0.47) | KMT2AALOX15BLMPMP22FOLH1 | |
| SCHEMBL1226605 | 0.85 | KMT2A (0.47) | KMT2AALOX15BLMPMP22FOLH1 | |
| SCHEMBL4795978 | 0.84 | NOD1 (0.47) | KMT2ANOD1 | |
| SCHEMBL22201756 | 0.84 | DPP4 (0.36) | KMT2AALOX15BLMPMP22FOLH1 | |
| SCHEMBL8633804 | 0.84 | KMT2A (0.47) | KMT2AALOX15BLMPMP22FOLH1 | |
| SCHEMBL5158281 | 0.84 | KMT2A (0.42) | KMT2AALOX15BLMPMP22FOLH1 | |
| SCHEMBL3364509 | 0.84 | KMT2A (0.42) | KMT2AALOX15BLMPMP22FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090106-A2 | ALKYLAMINES AND THEIR PRECURSORS AS SPECIFIC MODULATORS OF HUMAN GAMMA-DELTA T CELL FUNCTION | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2001-04-11 | — | — | EP | claimed |
| WO-2000000158-A9 | ALKYLAMINES AND THEIR PRECURSORS AS SPECIFIC MODULATORS OF HUMAN GAMMA-DELTA T CELL FUNCTION | BRIGHAM & WOMENS HOSPITAL (US) | 2000-06-22 | — | — | WO | claimed |
| WO-2000000158-A2 | ALKYLAMINES AND THEIR PRECURSORS AS SPECIFIC MODULATORS OF HUMAN GAMMA-DELTA T CELL FUNCTION | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2000-01-06 | — | — | WO | claimed |