SCHEMBL7762387

SCHEMBL7762387

[C]#CC=CCCCCCCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.48
TRPV1 Q8NER1 1/20 0.48
TSHR P16473 2/20 0.42
HMGCR P04035 2/20 0.42
TERT O14746 3/20 0.42
CYP1A2 P05177 2/20 0.42
MAPT P10636 2/20 0.42
CYP2C19 P33261 2/20 0.42
BLM P54132 2/20 0.42
HSD17B10 Q99714 2/20 0.42
FABP4 P15090 2/20 0.42
PTPN1 P18031 2/20 0.42
PPARG P37231 2/20 0.42
KMT2A Q03164 2/20 0.42
PPARD Q03181 2/20 0.42
PPARA Q07869 2/20 0.42
GMNN O75496 1/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760930 1.00 FAAH (0.48) FAAHTRPV1TSHRHMGCRTERT
SCHEMBL2005783 0.90
SCHEMBL10634058 0.80 FAAH (0.52) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL14760009 0.80 FAAH (0.52) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL10633939 0.80 FAAH (0.52) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL10634050 0.80 FAAH (0.52) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL14759666 0.80 FAAH (0.52) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL14759818 0.80 FAAH (0.52) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL14759955 0.80 FAAH (0.52) FAAHTRPV1TSHRTERTCYP1A2
SCHEMBL10629228 0.80 FAAH (0.52) FAAHTRPV1TSHRTERTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0720613-B1 VINYL ETHER URETHANE SILANES and titanates DSM NV (NL) 2001-04-04 EP disclosed
EP-0720613-A1 VINYL ETHER URETHANE SILANES DSM N.V. (NL) 1996-07-10 EP disclosed
WO-1995006650-A1 VINYL ETHER URETHANE SILANES DSM N.V. (NL) 1995-03-09 WO disclosed