SCHEMBL7762539

SCHEMBL7762539

CCC[SiH]1CCC([C@H]2CC[C@H](CCCCc3ccc(F)cc3)CC2)CC1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.34
CYP2D6 P10635 1/20 0.33
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7762546 1.00 MAOB (0.34) MAOBCYP2D6PPARGPPARA
SCHEMBL7762543 1.00 MAOB (0.34) MAOBCYP2D6PPARGPPARA
SCHEMBL7762604 0.93 ITGB3 (0.37)
SCHEMBL7762610 0.93 ITGB3 (0.37)
SCHEMBL7762618 0.93 ITGB3 (0.37)
SCHEMBL8003359 0.91 MAOB (0.42) MAOB
SCHEMBL8003360 0.91 MAOB (0.42) MAOB
SCHEMBL8003365 0.91 MAOB (0.42) MAOB
SCHEMBL7769784 0.90 HRH3 (0.33) MAOB
SCHEMBL7769781 0.90 HRH3 (0.33) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727428-B1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHINETSU CHEMICAL CO (JP) 2001-06-06 EP disclosed
US-5665271-A Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-09-09 US disclosed
EP-0727428-A1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-08-21 EP disclosed