Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 18/20 | 0.61 |
| ▸ | GGPS1 | O95749 | 9/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15452862 | 0.87 | FDPS (0.76) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL9313278 | 0.85 | FDPS (0.77) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL9313105 | 0.82 | FDPS (0.74) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL9323797 | 0.78 | FDPS (0.64) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL3025088 | 0.78 | FDPS (0.37) | FDPSGGPS1PDE3A | |
| SCHEMBL4736433 | 0.76 | FDPS (1.00) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL3411395 | 0.76 | FDPS (1.00) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL6666195 | 0.76 | FDPS (0.61) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL21985091 | 0.76 | FDPS (0.68) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL2455283 | 0.76 | FDPS (0.65) | FDPSGGPS1PDE3ALMNAADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | claimed |
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |