Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25784184 | 0.86 | SMN1; SMN2 (0.55) | TDP1ALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL25784185 | 0.83 | SMN1; SMN2 (0.47) | TDP1ALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL7762843 | 0.81 | TDP1 (0.44) | TDP1ALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL7762897 | 0.79 | ALDH1A1 (0.41) | TDP1ALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL85657 | 0.79 | PDE7A (0.50) | TDP1ALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL30279254 | 0.75 | SMN1; SMN2 (0.50) | TDP1ALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL395055 | 0.75 | SMN1; SMN2 (0.50) | TDP1ALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL30317899 | 0.73 | PTPRC (0.54) | TDP1ALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL3277269 | 0.73 | PTPRC (0.54) | TDP1ALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL3523467 | 0.73 | ALDH1A1 (0.58) | TDP1ALDH1A1CYP3A4TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701554-B1 | NOVEL COMPOUNDS HAVING A BENZISOSELEN-AZOLINE AND -AZINE STRUCTURE, METHOD FOR PREPARING SAME AND THERAPEUTIC USES THEREOF | OXIS ISLE OF MAN LTD (GB) | 2001-06-27 | — | — | EP | disclosed |
| WO-1995027706-A1 | NOVEL COMPOUNDS HAVING A BENZISOSELEN-AZOLINE AND -AZINE STRUCTURE, METHOD FOR PREPARING SAME AND THERAPEUTIC USES THEREOF | OXIS INTERNATIONAL S.A. (FR) | 1995-10-19 | — | — | WO | disclosed |