Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL8632311 | 0.87 | TET2 (0.36) | HMGCRCHRM1TBXA2RADRA1ATET2 | |
| SCHEMBL446370 | 0.87 | — | — | |
| Water SCHEMBL27488838 | 0.84 | — | — | |
| Oxalic Acid SCHEMBL1050270 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL17772996 | 0.72 | HMGCR (0.55) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| Oxalic Acid SCHEMBL30172492 | 0.67 | ALDH1A1 (0.37) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| Oxalic Acid SCHEMBL10594364 | 0.67 | ALDH1A1 (0.41) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL8724702 | 0.67 | — | — | |
| SCHEMBL6562039 | 0.67 | ALDH1A1 (0.37) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL3457363 | 0.67 | TSHR (0.36) | ALDH1A1TSHRHMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068793-A1 | CLEANING AGENT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-09-20 | — | — | WO | disclosed |