Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 4/20 | 0.67 |
| ▸ | CDC25B | P30305 | 2/20 | 0.67 |
| ▸ | OSBP | P22059 | 1/20 | 0.47 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764764 | 1.00 | CDC25A (0.67) | CDC25ACDC25BOSBPOSBP2GPBAR1 | |
| SCHEMBL7764767 | 1.00 | CDC25A (0.67) | CDC25ACDC25BOSBPOSBP2GPBAR1 | |
| SCHEMBL7763381 | 1.00 | CDC25A (0.67) | CDC25ACDC25BOSBPOSBP2GPBAR1 | |
| SCHEMBL26324654 | 0.88 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL17888102 | 0.88 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL14371762 | 0.88 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL14107828 | 0.88 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL29067231 | 0.88 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL26322309 | 0.88 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2NPC1L1 | |
| SCHEMBL9010519 | 0.86 | CDC25A (0.76) | CDC25ACDC25BOSBPOSBP2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854138-B1 | Vitamin D3 derivative and production process thereof | TEIJIN LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-6177586-B1 | USEFUL AS A PHARMACEUTICAL SUCH AS AN AGENT FOR PROMOTING BONE FORMATION, AN AGENT FOR SUPPRESSING PROLIFERATION OF TUMOR CELLS, AN AGENT FOR HIGH CALCIUM BLOOD DISEASES, AND AN IMMUNOSUPPRESSION AGENT | TEIJIN LIMITED (JP) | 2001-01-23 | — | — | US | disclosed |
| US-5986112-A | STEROID DERIVATIVES AS ANTITUMOR AGENTS AND BLOOD METAL CONCENTRATES | TEIJIN LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0854138-A2 | Vitamin D3 derivative and production process thereof | TEIJIN LIMITED (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5719297-A | Vitamin D3 derivatives and production process thereof | TEIJIN LIMITED (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0712843-A1 | VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1996-05-22 | — | — | EP | disclosed |