Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 8/20 | 0.76 |
| ▸ | CDC25B | P30305 | 6/20 | 0.76 |
| ▸ | OSBP | P22059 | 1/20 | 0.48 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.48 |
| ▸ | VDR | P11473 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14371762 | 0.91 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2VDR | |
| SCHEMBL29067231 | 0.91 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2VDR | |
| SCHEMBL26322309 | 0.91 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2VDR | |
| SCHEMBL14107828 | 0.91 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2VDR | |
| SCHEMBL26324654 | 0.91 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2VDR | |
| SCHEMBL17888102 | 0.91 | CDC25A (0.74) | CDC25ACDC25BOSBPOSBP2VDR | |
| SCHEMBL7763377 | 0.86 | CDC25A (0.67) | CDC25ACDC25BOSBPOSBP2GPBAR1 | |
| SCHEMBL9777571 | 0.86 | CDC25A (0.67) | CDC25ACDC25BOSBPOSBP2GPR183 | |
| SCHEMBL7764764 | 0.86 | CDC25A (0.67) | CDC25ACDC25BOSBPOSBP2GPBAR1 | |
| SCHEMBL9777599 | 0.86 | CDC25A (0.67) | CDC25ACDC25BOSBPOSBP2GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188064-B2 | Reducing cell differentiation of adipocyte; reducing body fat | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188064-B2 | Reducing cell differentiation of adipocyte; reducing body fat | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-05-29 | — | — | US | disclosed |
| EP-1641466-B1 | 2-METHYLENE-19-NOR-20(S)-25-METHYL-1ALPHA-HYDROXYCALCIFEROL AND ITS USES | WISCONSIN ALUMNI RES FOUND (US) | 2007-01-03 | — | — | EP | disclosed |