Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 5/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | KLK7 | P49862 | 2/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.55 |
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763637 | 1.00 | MAPT (0.57) | MAPTCTSSCTSKKLK7KLK5 | |
| SCHEMBL16798514 | 0.94 | MAPT (0.61) | MAPTCTSSCTSKKLK7KLK5 | |
| SCHEMBL16798512 | 0.94 | MAPT (0.61) | MAPTCTSSCTSKKLK7KLK5 | |
| SCHEMBL9504309 | 0.93 | MAPT (0.65) | MAPTKLK7KLK5MMP1MMP3 | |
| SCHEMBL6621271 | 0.90 | MAPT (0.60) | MAPTCTSSCTSKKLK7KLK5 | |
| SCHEMBL4602404 | 0.90 | MAPT (0.60) | MAPTCTSSCTSKKLK7KLK5 | |
| SCHEMBL1024713 | 0.90 | MAPT (0.60) | MAPTCTSSCTSKKLK7KLK5 | |
| SCHEMBL30962415 | 0.90 | MAPT (0.60) | MAPTCTSSCTSKKLK7KLK5 | |
| SCHEMBL6241676 | 0.89 | SYK (0.61) | MAPTCTSSCTSKKLK7KLK5 | |
| SCHEMBL6290849 | 0.87 | MAPT (0.52) | MAPTCTSSCTSKKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |