Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | KLK7 | P49862 | 2/20 | 0.64 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.64 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP3 | P08254 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.56 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16798512 | 0.97 | MAPT (0.61) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL16798514 | 0.97 | MAPT (0.61) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL7763641 | 0.93 | MAPT (0.57) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL7763637 | 0.93 | MAPT (0.57) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL30902907 | 0.92 | MAPT (0.65) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL17133648 | 0.91 | MAPT (0.64) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL7316805 | 0.91 | MAPT (0.64) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL17309872 | 0.90 | MAPT (0.68) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL2334326 | 0.90 | MAPT (0.68) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL2334319 | 0.90 | MAPT (0.68) | MAPTKLK7KLK5ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276436-B1 | PHOSPHINIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-16 | — | — | EP | disclosed |