Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1037894 | 1.00 | LMNA (0.31) | LMNAMC4RSMN1; SMN2SERPINE1 | |
| SCHEMBL7360219 | 1.00 | LMNA (0.31) | LMNAMC4RSMN1; SMN2SERPINE1 | |
| SCHEMBL906181 | 0.88 | SERPINE1 (0.38) | SMN1; SMN2SERPINE1 | |
| SCHEMBL37491 | 0.88 | SERPINE1 (0.42) | LMNASMN1; SMN2SERPINE1 | |
| SCHEMBL6735892 | 0.88 | SERPINE1 (0.42) | LMNASMN1; SMN2SERPINE1 | |
| SCHEMBL1069661 | 0.88 | SERPINE1 (0.38) | SMN1; SMN2SERPINE1 | |
| SCHEMBL166248 | 0.88 | SERPINE1 (0.42) | LMNASMN1; SMN2SERPINE1 | |
| SCHEMBL9166161 | 0.88 | SERPINE1 (0.38) | SMN1; SMN2SERPINE1 | |
| SCHEMBL14778899 | 0.88 | — | — | |
| SCHEMBL6666251 | 0.87 | CHRNA7 (0.32) | LMNAMC4RSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893427-B1 | Process for the preparation of cyclobutan-1,2-dicarboxylic acid esters | LONZA AG (CH) | 2001-09-19 | — | — | EP | claimed |
| EP-0893427-A1 | Process for the preparation of cyclobutan-1,2-dicarboxylic acid esters | LONZA A.G. (CH) | 1999-01-27 | — | — | EP | claimed |
| EP-0893427-B1 | Process for the preparation of cyclobutan-1,2-dicarboxylic acid esters | LONZA AG (CH) | 2001-09-19 | — | — | EP | disclosed |
| EP-0893427-A1 | Process for the preparation of cyclobutan-1,2-dicarboxylic acid esters | LONZA A.G. (CH) | 1999-01-27 | — | — | EP | disclosed |
| EP-0000403-B1 | BISPHOSPHINIC METAL COMPLEXES, PROCESS FOR THEIR PREPARATION, HYDROGENATION CATALYSTS FROM THESE COMPOUNDS, AND A HYDROGENATION PROCESS EMPLOYING THESE CATALYSTS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-06-17 | — | — | EP | disclosed |
| EP-0000403-A1 | Bisphosphinic metal complexes, process for their preparation, hydrogenation catalysts from these compounds, and a hydrogenation process employing these catalysts | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-01-24 | — | — | EP | disclosed |