Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126096 | 0.88 | — | — | |
| Water SCHEMBL28164140 | 0.85 | CYP4F2 (0.52) | CYP4F2CYP4A11MEN1KMT2AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27789132 | 0.85 | CYP4F2 (0.52) | CYP4F2CYP4A11MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL29726512 | 0.85 | CYP4F2 (0.52) | CYP4F2CYP4A11MEN1KMT2AALDH1A1 | |
| SCHEMBL28865223 | 0.85 | CYP4F2 (0.52) | CYP4F2CYP4A11MEN1KMT2AALDH1A1 | |
| Alcohol SCHEMBL12506185 | 0.83 | CYP4F2 (0.55) | CYP4F2CYP4A11MEN1KMT2AALDH1A1 | |
| SCHEMBL15740594 | 0.77 | MEN1 (0.43) | CYP4F2CYP4A11MEN1KMT2AALDH1A1 | |
| SCHEMBL28662844 | 0.75 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1PKMLMNA | |
| SCHEMBL7065729 | 0.74 | MEN1 (0.44) | CYP4F2CYP4A11MEN1KMT2AALDH1A1 | |
| SCHEMBL1970967 | 0.74 | CYP4F2 (0.43) | CYP4F2CYP4A11MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095043-A1 | TRIOXANE DERIVATIVES | The Hong Kong University of Science & Technology (HK) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000004025-A1 | ANTIPARASITIC ARTEMISININ DERIVATIVES (ENDOPEROXIDES) | THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2000-01-27 | — | — | WO | disclosed |
| WO-2000004026-A1 | TRIOXANE DERIVATIVES | THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2000-01-27 | — | — | WO | disclosed |