Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | MC5R | P33032 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | MC1R | Q01726 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349391 | 1.00 | NTMT1 (0.51) | NTMT1MMP1MMP3MMP9TRPV1 | |
| Hydrochloric Acid SCHEMBL7759028 | 0.99 | NTMT1 (0.51) | NTMT1MMP1MMP3MMP9TRPV1 | |
| Hydrochloric Acid SCHEMBL8344064 | 0.99 | NTMT1 (0.51) | NTMT1MMP1MMP3MMP9TRPV1 | |
| Hydrochloric Acid SCHEMBL8342864 | 0.95 | NTMT1 (0.50) | NTMT1MMP1MMP3MMP9MEN1 | |
| Hydrochloric Acid SCHEMBL7764068 | 0.95 | NTMT1 (0.50) | NTMT1MMP1MMP3MMP9MEN1 | |
| SCHEMBL7765678 | 0.93 | NTMT1 (0.49) | NTMT1MMP1MMP3MMP9TRPV1 | |
| SCHEMBL7761871 | 0.93 | NTMT1 (0.49) | NTMT1MMP1MMP3MMP9TRPV1 | |
| Hydrochloric Acid SCHEMBL7761875 | 0.93 | NTMT1 (0.48) | NTMT1MMP1MMP3MMP9MEN1 | |
| Hydrochloric Acid SCHEMBL7761862 | 0.93 | NTMT1 (0.48) | NTMT1MMP1MMP3MMP9MEN1 | |
| SCHEMBL8343138 | 0.88 | NTMT1 (0.58) | NTMT1MEN1KMT2AKDM4EGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808839-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5883121-A | INHIBITING ACTIVITY AGAINST CATHEPSIN, AND IS USEFUL FOR PREVENTION AND TREATMENT OF OSTEOPATHY SUCH AS OSTEOPOROSIS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0808839-A1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF, AND DRUGS CONTAINING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1997-11-26 | — | — | EP | disclosed |