Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | MPL | P40238 | 6/20 | 0.50 |
| ▸ | CTRC | Q99895 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 3/20 | 0.49 |
| ▸ | MMP14 | P50281 | 2/20 | 0.49 |
| ▸ | CASP6 | P55212 | 2/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | ATIC | P31939 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | IDE | P14735 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763972 | 1.00 | CYP1A2 (0.63) | CYP1A2MPLCTRCNSD2MMP14 | |
| SCHEMBL4790578 | 0.77 | CYP1A2 (0.64) | CYP1A2MPLCTRCNSD2MMP14 | |
| SCHEMBL4759609 | 0.77 | CYP1A2 (0.64) | CYP1A2MPLCTRCNSD2MMP14 | |
| SCHEMBL6654290 | 0.76 | CTRB1 (0.82) | CYP1A2MPLCTRCNSD2CTRB1 | |
| SCHEMBL7764792 | 0.75 | MPL (0.70) | CYP1A2MPLCTRCNSD2MMP14 | |
| SCHEMBL12960419 | 0.75 | CYP1A2 (0.82) | CYP1A2MPLCTRCNSD2CTRB1 | |
| SCHEMBL11754648 | 0.74 | CYP1A2 (0.67) | CYP1A2MPLCTRCNSD2MMP14 | |
| SCHEMBL5148283 | 0.74 | CYP1A2 (0.67) | CYP1A2MPLCTRCNSD2MMP14 | |
| SCHEMBL3453258 | 0.74 | CYP1A2 (0.67) | CYP1A2MPLCTRCNSD2CTRB1 | |
| SCHEMBL344112 | 0.74 | CYP1A2 (0.63) | CYP1A2MPLCTRCNSD2MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104674-A1 | O,o'-dihydroxy azo dyes as medicinal components with TPO-agonistic or -synergetic activity | Curacyte AG (DE) | 2001-06-06 | — | — | EP | claimed |
| EP-1104674-A1 | O,o'-dihydroxy azo dyes as medicinal components with TPO-agonistic or -synergetic activity | Curacyte AG (DE) | 2001-06-06 | — | — | EP | disclosed |