2,4-Dinitrophenol

2,4-Dinitrophenol

SCHEMBL77643

O=[N+]([O-])c1ccc(O)c([N+](=O)[O-])c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 3/20 1.00
MAPK1 P28482 3/20 1.00
ALDH1A1 P00352 3/20 1.00
HPGD P15428 2/20 1.00
TP53 P04637 1/20 1.00
TSHR P16473 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
ALOX15 P16050 2/20 0.62
HSD17B10 Q99714 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
GAA P10253 1/20 0.62
THRB P10828 1/20 0.62
TDP1 Q9NUW8 2/20 0.61
KDM4E B2RXH2 3/20 0.59
MAPT P10636 3/20 0.59
HIF1A Q16665 2/20 0.59
CYP1A2 P05177 2/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
TTR P02766 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,4-Dinitrophenol SCHEMBL1517938 1.00 GPR35 (1.00) GPR35MAPK1ALDH1A1HPGDTP53
2,4-Dinitrophenol SCHEMBL29361027 1.00 GPR35 (1.00) GPR35MAPK1ALDH1A1HPGDTP53
2,4-Dinitrophenol SCHEMBL3499025 0.98 GPR35 (0.96) GPR35MAPK1ALDH1A1HPGDTP53
2,4-Dinitrophenol SCHEMBL10714787 0.98 GPR35 (0.96) GPR35MAPK1ALDH1A1HPGDTP53
2,4-Dinitrophenol SCHEMBL31621294 0.98 GPR35 (0.96) GPR35MAPK1ALDH1A1HPGDTP53
2,4-Dinitrophenol SCHEMBL16553313 0.98 GPR35 (0.96) GPR35MAPK1ALDH1A1HPGDTP53
2,4-Dinitrophenol SCHEMBL4427609 0.98 GPR35 (0.96) GPR35MAPK1ALDH1A1HPGDTP53
2,4-Dinitrophenol SCHEMBL3499026 0.98 GPR35 (0.96) GPR35MAPK1ALDH1A1HPGDTP53
2,4-Dinitrophenol SCHEMBL1525711 0.98 GPR35 (0.96) GPR35MAPK1ALDH1A1HPGDTP53
2,4-Dinitrophenol SCHEMBL30315863 0.98 GPR35 (0.96) GPR35MAPK1ALDH1A1HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13543 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106971-A1 FLOW CELLS AND METHODS FOR ANALYZING A BIOLOGICAL COMPONENT Cellanome, Inc. (US) 2026-05-21 WO claimed
CN-122060811-A Method for producing agricultural tryptophan by fermentation and application thereof 烟台泓源生物肥料有限公司 2026-05-19 CN claimed
CN-122036449-A Tetravinylbenzyl indene derivative, preparation method thereof, and thermosetting hydrocarbon resin of tetravinylbenzyl indene derivative and application thereof 山东星顺新材料股份有限公司 2026-05-15 CN claimed
CN-122036813-A Schiff base cobalt complex, preparation method and application 安徽大学 2026-05-15 CN claimed
CN-122028923-A Use of coagulation promoting factors in regulating lipid homeostasis 北京大学 2026-05-12 CN claimed
US-12622925-B2 Edible enterosorbents used to mitigate acute exposures to ingestible environmental toxins following outbreaks, natural disasters and emergencies NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2026-05-12 US claimed
US-20260108476-A1 2,4 DNP and Prodrugs Thereof for Treatment of Cancer MITOCHON PHARMACEUTICALS, INC. (US) 2026-04-23 US claimed
EP-4724455-A1 MULTIVALENT BINDING UNIT MODIFIED DIDEOXYNUCLEOTIDE TRIPHOSPHATES AND METHODS OF MAKING AND USING THE SAME ILLUMINA, INC. (US) 2026-04-15 EP claimed
EP-4086242-B1 5-[(2,4-DINITROPHENOXY)METHYL]-1-METHYL-2-NITRO-L H-IMIDAZOLE AND ITS PHARMACEUTICAL USE RIVUS PHARMACEUTICALS INC (US) 2026-04-08 EP claimed
CN-121574042-A Preparation method of chloromethyl styrene 江苏扬农化工集团有限公司 2026-02-27 CN claimed
US-4247481-A RANEY CATALYSTS, HYDROGENATION OF NITRILES MONSANTO COMPANY (US) 1981-01-27 US claimed
EP-0011844-A1 Coupling components for oxidizing hair dyes, their preparation and hair dyes containing them Henkel Kommanditgesellschaft auf Aktien (DE) 1980-06-11 EP claimed
WO-1980000791-A1 B-GLUCURONIDASE ACTIVITY AND/OR PH-DEPENDENT PHARMACEUTICALS AND THEIR METHODS OF PRODUCTION AND USE FOR SELECTIVE TREATMENT OF DISEASES SCHWIMMER A (US) 1980-05-01 WO claimed
US-4170669-A ACID- OR BASE-SOLUBILE OKADA ICHIRO (JP) 1979-10-09 US claimed
US-4145549-A CYCLIZATION, SOLVOLYSIS SANDOZ LTD. (CH) 1979-03-20 US claimed
US-4123614-A USED IN DETECTION AND MEASUREMENT OF BIOLOGICAL SYSTEMS AND/OR COMPONENTS SYNTEX (U.S.A.) INC. (US) 1978-10-31 US claimed
US-4123464-A Process for the preparation of aldehydes HOFFMANN-LA ROCHE INC. (US) 1978-10-31 US claimed
US-4115652-A Process for the preparation of amino-nitrophenols BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US claimed
US-4000139-A ERGOT ALKALOID INTERMEDIATES SANDOZ LTD. (CH) 1976-12-28 US claimed
US-3953297-A Determination of amylase PIERCE CHEMICAL COMPANY (US) 1976-04-27 US claimed