⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764316 | 0.85 | TSHR (0.35) | — | |
| SCHEMBL2361742 | 0.84 | — | — | |
| SCHEMBL319743 | 0.78 | — | — | |
| SCHEMBL2968538 | 0.76 | TSHR (0.30) | — | |
| SCHEMBL15194261 | 0.74 | — | — | |
| SCHEMBL2967467 | 0.72 | — | — | |
| SCHEMBL6437687 | 0.71 | — | — | |
| SCHEMBL6437685 | 0.71 | — | — | |
| SCHEMBL6790303 | 0.70 | — | — | |
| SCHEMBL2361867 | 0.70 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705838-B1 | Process for the preparation of silane polysulfides | CROMPTON CORP (US) | 2001-05-23 | — | — | EP | disclosed |
| US-5596116-A | Process for the preparation of silane polysulfides | OSI SPECIALTIES, INC. (US) | 1997-01-21 | — | — | US | disclosed |
| EP-0705838-A2 | Process for the preparation of silane polysulfides | OSi SPECIALTIES, INC. (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5489701-A | REACTING SULFUR AND A HALOHYDROCARBYLALKOXYSILANE WITH THE REACTION PRODUCT OF HYDROGEN SULFIDE GAS AND A METAL ALKOXIDE SOLUTION | OSI SPECIALTIES, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5466848-A | Sulfiding sodium ethoxide with hydrogen sulfide to make sodium sulfide; reacting with sulfur to tetrasulfide; reacting with halohydrocarbylalkoxysilane | OSI SPECIALTIES, INC. (US) | 1995-11-14 | — | — | US | disclosed |