SCHEMBL2968538

SCHEMBL2968538

CCC[CH][Si](OCC)(OCC)OCC

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6790303 0.87
SCHEMBL6785811 0.87
SCHEMBL2361815 0.84 TSHR (0.36) TSHRALDH1A1
SCHEMBL2361158 0.82 TSHR (0.37) TSHRALDH1A1
SCHEMBL7760552 0.81
SCHEMBL3761507 0.80 TSHR (0.41) TSHR
SCHEMBL9312908 0.80 TSHR (0.41) TSHR
SCHEMBL7764826 0.77 ADRB2 (0.35) TSHRALDH1A1
SCHEMBL329896 0.77
SCHEMBL7764300 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103360545-A Functionalized polymer, rubber composition and pneumatic tire GOODYEAR TIRE & RUBBER 2013-10-23 CN claimed
EP-0632099-B1 Organopolysiloxane and method for the preparation thereof DOW CORNING TORAY SILICONE (JP) 1997-11-12 EP claimed
EP-0639606-B1 Organopolysiloxane and method for the preparation thereof DOW CORNING TORAY SILICONE (JP) 1997-05-21 EP claimed
US-5468827-A Epoxy-functional MQ organopolysiloxanes DOW CORNING TORAY SILICON CO., LTD. (JP) 1995-11-21 US claimed
US-5422412-A Organopolysiloxane and method for the preparation thereof DOW CORNING TORAY SILICON CO., LTD (JP) 1995-06-06 US claimed
EP-0639606-A1 Organopolysiloxane and method for the preparation thereof Dow Corning Toray Silicone Company, Limited (JP) 1995-02-22 EP claimed
EP-0632099-A2 Organopolysiloxane and method for the preparation thereof Dow Corning Toray Silicone Company, Limited (JP) 1995-01-04 EP claimed
WO-2024106213-A1 METHOD FOR PRODUCING DISILOXANE COMPOUND 信越化学工業株式会社 2024-05-23 WO disclosed
US-11733609-B2 Silicon-containing underlayers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-08-22 US disclosed
CN-113121827-B Modified polymethylhydrosiloxane, terminal modified conjugated diene-vinyl aromatic hydrocarbon copolymer, and synthetic method and application thereof 奇美实业股份有限公司 2023-04-14 CN disclosed
US-11360387-B2 Silicon-containing underlayers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2022-06-14 US disclosed
US-20210397093-A1 SILICON-CONTAINING UNDERLAYERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2021-12-23 US disclosed
CN-113121829-A Terminal-modified conjugated diene-vinyl aromatic hydrocarbon copolymer, process for producing the same, rubber composition, and tire 奇美实业股份有限公司 2021-07-16 CN disclosed
US-5489701-A REACTING SULFUR AND A HALOHYDROCARBYLALKOXYSILANE WITH THE REACTION PRODUCT OF HYDROGEN SULFIDE GAS AND A METAL ALKOXIDE SOLUTION OSI SPECIALTIES, INC. (US) 1996-02-06 US disclosed
US-5486588-A Epoxy-functional organopolysiloxane from SiH polysiloxane, unsaturated epoxy compound and alkene DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) 1996-01-23 US disclosed
US-5468827-A Epoxy-functional MQ organopolysiloxanes DOW CORNING TORAY SILICON CO., LTD. (JP) 1995-11-21 US disclosed
US-5466848-A Sulfiding sodium ethoxide with hydrogen sulfide to make sodium sulfide; reacting with sulfur to tetrasulfide; reacting with halohydrocarbylalkoxysilane OSI SPECIALTIES, INC. (US) 1995-11-14 US disclosed
US-5422412-A Organopolysiloxane and method for the preparation thereof DOW CORNING TORAY SILICON CO., LTD (JP) 1995-06-06 US disclosed
EP-0639606-A1 Organopolysiloxane and method for the preparation thereof Dow Corning Toray Silicone Company, Limited (JP) 1995-02-22 EP disclosed
EP-0632099-A2 Organopolysiloxane and method for the preparation thereof Dow Corning Toray Silicone Company, Limited (JP) 1995-01-04 EP disclosed