Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16138541 | 0.76 | BCHE (0.30) | — | |
| SCHEMBL4904967 | 0.76 | KDM4E (0.57) | KDM4E | |
| Iodide SCHEMBL7769625 | 0.75 | KDM4E (0.56) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10998115 | 0.74 | — | — | |
| SCHEMBL19361321 | 0.74 | — | — | |
| SCHEMBL4904783 | 0.74 | SLC18A3 (0.39) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18459296 | 0.74 | NCF1 (0.34) | — | |
| SCHEMBL16218958 | 0.74 | NCF1 (0.30) | — | |
| Iodide SCHEMBL21002112 | 0.73 | CHRNA10 (0.38) | — | |
| Iodide SCHEMBL7768009 | 0.73 | KDM4E (0.60) | KDM4ECHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700916-B1 | CEPHEM COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTIBACTERIAL CONTAINING THE COMPOUND | OTSUKA KAGAKU KK (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5698544-A | ANTIBOIOTIC AGAINST METHICILLIN RESISTANCE STAPHYLOCOCCUS AUREUS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0700916-A1 | CEPHEM COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTIBACTERIAL CONTAINING THE COMPOUND | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |