Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 17/20 | 1.00 |
| ▸ | MTTP | P55157 | 16/20 | 1.00 |
| ▸ | SMO | Q99835 | 5/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764352 | 1.00 | APOB (1.00) | APOBMTTPSMO | |
| SCHEMBL7763181 | 0.93 | APOB (0.86) | APOBMTTPSMO | |
| SCHEMBL13591623 | 0.91 | APOB (0.83) | APOBMTTPSMO | |
| SCHEMBL10205353 | 0.86 | MTTP (1.00) | APOBMTTPSMO | |
| SCHEMBL4785948 | 0.86 | MTTP (1.00) | APOBMTTPSMO | |
| SCHEMBL7038523 | 0.86 | MTTP (1.00) | APOBMTTPSMO | |
| SCHEMBL13591619 | 0.85 | APOB (0.79) | APOBMTTPSMO | |
| SCHEMBL7760794 | 0.84 | APOB (0.76) | APOBMTTPSMO | |
| SCHEMBL7760803 | 0.84 | APOB (0.76) | APOBMTTPSMO | |
| SCHEMBL13591620 | 0.84 | APOB (0.75) | APOBMTTPSMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097129-A1 | N-BENZOCYCLOALKYL-AMIDE DERIVATIVES AND THEIR USE AS MEDICAMENTS | Novartis AG (CH) | 2001-05-09 | — | — | EP | disclosed |
| US-6197798-B1 | INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN | NOVARTIS AG (CH) | 2001-03-06 | — | — | US | disclosed |
| WO-2000005201-A1 | N-BENZOCYCLOALKYL-AMIDE DERIVATIVES AND THEIR USE AS MEDICAMENTS | NOVARTIS AG (CH) | 2000-02-03 | — | — | WO | disclosed |