Biphenyl

Biphenyl

SCHEMBL7764468

C=C(C)C(N)=O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.57
SMN1; SMN2 Q16637 3/20 0.52
MAPT P10636 3/20 0.52
LMNA P02545 1/20 0.45
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
BCAT2 O15382 1/20 0.43
DHODH Q02127 1/20 0.42
IKBKB O14920 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
PARP1 P09874 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PTGS2 P35354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29257169 0.87 TDP1 (0.67) TDP1SMN1; SMN2MAPTLMNAALDH1A1
Biphenyl SCHEMBL29002594 0.85 SMN1; SMN2 (0.56) SMN1; SMN2MAPTLMNAALDH1A1KDM4E
Biphenyl SCHEMBL28980207 0.85 SMN1; SMN2 (0.56) SMN1; SMN2MAPTLMNAALDH1A1KDM4E
Biphenyl SCHEMBL473586 0.85 SMN1; SMN2 (0.56) SMN1; SMN2MAPTLMNAALDH1A1KDM4E
Biphenyl SCHEMBL36673 0.85 SMN1; SMN2 (0.56) SMN1; SMN2MAPTLMNAALDH1A1KDM4E
Biphenyl SCHEMBL2670012 0.85 MAPT (0.61) TDP1SMN1; SMN2MAPTLMNAALDH1A1
Benzene SCHEMBL27845982 0.84 TDP1 (0.80) TDP1MAPTLMNAALDH1A1KDM4E
Benzene SCHEMBL28099155 0.84 TDP1 (0.80) TDP1MAPTLMNAALDH1A1KDM4E
Phenol SCHEMBL5613710 0.84 TDP1 (0.55) TDP1MAPTLMNAALDH1A1KDM4E
Phenol SCHEMBL11128761 0.84 TDP1 (0.55) TDP1MAPTLMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731188-A2 SYNTHETIC CELLS COMPRISING TNF-RELATED APOPTOSIS-INDUCING LIGAND (TRAIL) AND METHODS OF USING THE SAME Slingshot Biosciences, Inc. (US) 2026-04-29 EP disclosed
WO-2024263999-A2 SYNTHETIC CELLS COMPRISING TNF-RELATED APOPTOSIS-INDUCING LIGAND (TRAIL) AND METHODS OF USING THE SAME SLINGSHOT BIOSCIENCES, INC. (US) 2024-12-26 WO disclosed
EP-4423250-A1 HYDROGEL PARTICLES AS FEEDER CELLS AND AS SYNTHETIC ANTIGEN PRESENTING CELLS Slingshot Biosciences, Inc. (US) 2024-09-04 EP disclosed
WO-2023076629-A1 HYDROGEL PARTICLES AS FEEDER CELLS AND AS SYNTHETIC ANTIGEN PRESENTING CELLS SLINGSHOT BIOSCIENCES, INC. (US) 2023-05-04 WO disclosed
EP-0563403-B1 DISPLAY ELEMENT AND ITS MANUFACTURING METHOD SEIKO EPSON CORP (JP) 2001-05-30 EP disclosed
US-5769393-A Liquid crystal elements and method of producing same SEIKO EPSON CORPORATION (JP) 1998-06-23 US disclosed
EP-0563403-A1 DISPLAY ELEMENT AND ITS MANUFACTURING METHOD SEIKO EPSON CORPORATION (JP) 1993-10-06 EP disclosed