Biphenyl

Biphenyl

SCHEMBL473586

C=C(C)C(=O)O.C=C(C)C(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.56
MAPT P10636 2/20 0.56
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.45
PTGS2 P35354 1/20 0.45
TP53 P04637 1/20 0.45
PTPN1 P18031 1/20 0.45
PTPN11 Q06124 1/20 0.45
HPGD P15428 2/20 0.43
ABCC4 O15439 1/20 0.43
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
TSHR P16473 1/20 0.43
PTGS1 P23219 1/20 0.43
HTT P42858 1/20 0.43
AKR1C3 P42330 1/20 0.43
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
ERCC5 P28715 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL36673 1.00 SMN1; SMN2 (0.56) SMN1; SMN2MAPTALDH1A1KDM4EL3MBTL1
Biphenyl SCHEMBL29002594 1.00 SMN1; SMN2 (0.56) SMN1; SMN2MAPTALDH1A1KDM4EL3MBTL1
Biphenyl SCHEMBL28980207 1.00 SMN1; SMN2 (0.56) SMN1; SMN2MAPTALDH1A1KDM4EL3MBTL1
Biphenyl SCHEMBL9172718 0.97 SMN1; SMN2 (0.54) SMN1; SMN2MAPTALDH1A1KDM4EL3MBTL1
Biphenyl SCHEMBL10386000 0.97 SMN1; SMN2 (0.54) SMN1; SMN2MAPTALDH1A1KDM4EL3MBTL1
Biphenyl SCHEMBL7767446 0.97 SMN1; SMN2 (0.54) SMN1; SMN2MAPTALDH1A1KDM4EL3MBTL1
Tannin Pyrogallol SCHEMBL16192271 0.97 SMN1; SMN2 (0.60) SMN1; SMN2MAPTALDH1A1KDM4EL3MBTL1
Methacrylic Acid SCHEMBL28574988 0.97 SMN1; SMN2 (0.54) SMN1; SMN2MAPTALDH1A1KDM4EL3MBTL1
Methacrylic Acid SCHEMBL16192481 0.91 KMO (0.55) SMN1; SMN2MAPTKDM4EPTGS2ERCC5
Biphenyl SCHEMBL28486257 0.91 MAPT (0.48) SMN1; SMN2MAPTALDH1A1KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4721699-A1 COMPOSITE BULK BLOCK FOR MANUFACTURING PROSTHESIS, MANUFACTURING METHOD THEREFOR, AND PROSTHESIS MANUFACTURED THEREFROM Hass Co., Ltd. (KR) 2026-04-08 EP claimed
WO-2025127853-A1 COMPOSITE BULK BLOCK FOR DENTAL PROSTHESIS FABRICATION, MANUFACTURING METHOD THEREFOR, AND PROSTHESIS FABRICATED THEREFROM 주식회사 하스 2025-06-19 WO claimed
WO-2024248386-A1 COMPOSITE BULK BLOCK FOR MANUFACTURING PROSTHESIS, MANUFACTURING METHOD THEREFOR, AND PROSTHESIS MANUFACTURED THEREFROM 주식회사 하스 2024-12-05 WO claimed
US-11998409-B2 Dental composite blank and method for manufacturing same VERICOM CO., LTD. (KR) 2024-06-04 US claimed
EP-4360588-A1 BULK BLOCK FOR MANUFACTURING DENTAL PROSTHESIS Hass Co., Ltd. (KR) 2024-05-01 EP claimed
US-20240130934-A1 BULK BLOCK FOR MANUFACTURING DENTAL PROSTHESIS HASS CO., LTD. (KR) 2024-04-25 US claimed
CN-117693320-A Large block for manufacturing dental prosthesis 株式会社哈斯 2024-03-12 CN claimed
WO-2024005249-A1 METHOD FOR MANUFACTURING MEDICAL RESIN FILLER HAVING FLUORESCENCE 정인선 2024-01-04 WO claimed
WO-2023158154-A1 ADDITIVE-MANUFACTURING-TYPE HYBRID CERAMIC DENTAL PROSTHESIS 주식회사 하스 2023-08-24 WO claimed
US-11591427-B2 Dental composite comprising glass ceramic HASS CO., LTD. (KR) 2023-02-28 US claimed
US-20100292360-A1 Pre-Treated Acid-Reactive Fillers and Their Use in Dental Applications PENTRON CLINICAL TECHNOLOGIES, L.L.C. (US) 2010-11-18 US claimed
WO-2010110798-A1 CURABLE ZIRCONIA ADHESIVE COMPOSITIONS FOR DENTAL RESTORATIONS BISCO, INC. (US) 2010-09-30 WO claimed
US-20100247738-A1 CURABLE ZIRCONIA ADHESIVE COMPOSITIONS FOR DENTAL RESTORATIONS BISCO, INC. (US) 2010-09-30 US claimed
EP-2117494-A1 DENTAL PRIMER ADHESIVE SYSTEM AND OPTIONAL HYDROPHOBIC RESIN Bisco, Inc. (US) 2009-11-18 EP claimed
EP-2114357-A1 DUAL APPLICATION MODE SELF-ETCH DENTAL ADHESIVES COMPATIBLE WITH SELF-CURED AND DUAL-CURED COMPOSITES Bisco, Inc. (US) 2009-11-11 EP claimed
WO-2008094925-A1 DENTAL PRIMER ADHESIVE SYSTEM AND OPTIONAL HYDROPHOBIC RESIN BISCO, INC. (US) 2008-08-07 WO claimed
WO-2008094923-A1 DUAL APPLICATION MODE SELF-ETCH DENTAL ADHESIVES COMPATIBLE WITH SELF-CURED AND DUAL-CURED COMPOSITES BISCO, INC. (US) 2008-08-07 WO claimed
US-20080182922-A1 Dual Application Mode Self-Etch Dental Adhesives Compatible with Self-Cured and Dual-Cured Composites BISCO, INC. (US) 2008-07-31 US claimed
US-20080182921-A1 Dental Primer Adhesive System and Optional Hydrophobic Resin BISCO, INC. (US) 2008-07-31 US claimed
US-6147137-A POLYMERIZABLE ACID, METHACRYLATE AND 1,1,1-TRIMETHYLOLPROPANE TRIMETHACRYLATE MONOMERS; SHELF-LIFE, STORAGE STABILITY JENERIC/PENTRON INCORPORATED (US) 2000-11-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100247738-A1 CURABLE ZIRCONIA ADHESIVE COMPOSITIONS FOR DENTAL RESTORATIONS ZYX, CAD, ILK SMN1; SMN2 3054/4885MAPT 2028/4885ALDH1A1 1809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.