Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Hexanol SCHEMBL7509890 | 1.00 | LMNA (0.77) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 1-Heptanol SCHEMBL12476248 | 1.00 | LMNA (0.77) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Decanol SCHEMBL28195522 | 1.00 | LMNA (0.77) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Octanol SCHEMBL9852482 | 1.00 | LMNA (0.77) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Cetostearyl Alcohol SCHEMBL6264738 | 1.00 | LMNA (0.77) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Tridecan-1-Ol SCHEMBL27841409 | 1.00 | LMNA (0.77) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Dodecanol SCHEMBL28254828 | 1.00 | LMNA (0.77) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Dodecanol SCHEMBL6230418 | 0.97 | LMNA (0.72) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Octanol SCHEMBL20527757 | 0.97 | LMNA (0.72) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Octanol SCHEMBL27298986 | 0.97 | LMNA (0.72) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087236-A2 | TOPICAL ADMINISTRATION OF PHARMACOLOGICAL COMPOSITIONS FOR NON-SYSTEMIC TREATMENT OF PRURITUS | KLEIN GERALD L (US) | 2001-11-22 | — | — | WO | disclosed |