Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536567 | 0.76 | PARP1 (0.34) | — | |
| SCHEMBL7729865 | 0.72 | SLC6A2 (0.33) | ALDH1A1 | |
| SCHEMBL1535614 | 0.70 | KCNA3 (0.56) | MEN1KMT2AALDH1A1KDM4ERECQL | |
| SCHEMBL22297235 | 0.70 | KCNA3 (0.56) | MEN1KMT2AALDH1A1KDM4ERECQL | |
| SCHEMBL5897061 | 0.70 | KCNA3 (0.56) | MEN1KMT2AALDH1A1KDM4ERECQL | |
| SCHEMBL10711044 | 0.70 | KCNA3 (0.56) | MEN1KMT2AALDH1A1KDM4ERECQL | |
| SCHEMBL11134448 | 0.70 | KCNA3 (0.56) | MEN1KMT2AALDH1A1KDM4ERECQL | |
| SCHEMBL12703538 | 0.68 | KDM4E (0.61) | KDM4ERECQLMAPTL3MBTL1MAPK1 | |
| SCHEMBL3611926 | 0.68 | KDM4E (0.61) | KDM4ERECQLMAPTL3MBTL1MAPK1 | |
| SCHEMBL6536500 | 0.68 | ATM (0.34) | OPRM1OPRL1ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112264-A1 | POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-07-04 | — | — | EP | claimed |
| WO-2000015630-A1 | POLYALKOXYLATED NAPHTHOPYRANS | PPG INDUSTRIES OHIO, INC. (US) | 2000-03-23 | — | — | WO | claimed |
| EP-1112264-A1 | POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015630-A1 | POLYALKOXYLATED NAPHTHOPYRANS | PPG INDUSTRIES OHIO, INC. (US) | 2000-03-23 | — | — | WO | disclosed |