Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21378238 | 0.83 | ALDH1A1 (0.49) | MAPK1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL21844090 | 0.81 | ALDH1A1 (0.50) | MAPK1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL14925983 | 0.76 | ALDH1A1 (0.43) | MAPK1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL20022608 | 0.75 | ALDH1A1 (0.45) | MAPK1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL16794181 | 0.71 | DRD3 (0.52) | MAPK1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL16412280 | 0.71 | ALDH1A1 (0.47) | MAPK1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL22307727 | 0.70 | GAA (0.49) | MAPK1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL31305777 | 0.68 | ALDH1A1 (0.41) | MAPK1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL18152850 | 0.68 | MAPK1 (0.50) | MAPK1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL29200214 | 0.66 | ALDH1A1 (0.55) | MAPK1KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001092285-A1 | NOVEL OLIGONUCLEOTIDE COMPOUNDS HAVING PYRROLIZINE DERIVATIVES, PROCESSES FRO PREPARING THEM, COMPOSITIONS CONTAINING THEM AND USES THEREOF IN TREATMENT, DIAGNOSIS AND ANALYSIS OF GENE-RELATED DISEASES | GENECHEM INC. (KR) | 2001-12-06 | — | — | WO | disclosed |