Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 4/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765817 | 1.00 | CDC25A (0.40) | CDC25ACDC25BCYP17A1GPBAR1BACE1 | |
| SCHEMBL7764298 | 0.87 | CDC25A (0.38) | CDC25ACDC25BCYP17A1GPBAR1BACE1 | |
| SCHEMBL10440704 | 0.87 | CDC25A (0.40) | CDC25ACDC25BCYP17A1GPBAR1 | |
| SCHEMBL8211097 | 0.87 | CDC25A (0.40) | CDC25ACDC25BCYP17A1GPBAR1 | |
| SCHEMBL8209307 | 0.87 | CDC25A (0.40) | CDC25ACDC25BCYP17A1GPBAR1 | |
| SCHEMBL8674922 | 0.87 | CDC25A (0.40) | CDC25ACDC25BCYP17A1GPBAR1 | |
| SCHEMBL14107826 | 0.87 | CDC25A (0.40) | CDC25ACDC25BCYP17A1GPBAR1 | |
| SCHEMBL8209310 | 0.87 | CDC25A (0.40) | CDC25ACDC25BCYP17A1GPBAR1 | |
| SCHEMBL7764308 | 0.87 | CDC25A (0.38) | CDC25ACDC25BCYP17A1GPBAR1BACE1 | |
| SCHEMBL7764301 | 0.87 | CDC25A (0.38) | CDC25ACDC25BCYP17A1GPBAR1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102789-A1 | MONOCYCLIC COMPOUNDS HAVING NK-2 ANTAGONIST ACTION AND COMPOSITIONS CONTAINING THEM | Menarini Ricerche S.p.A. (IT) | 2001-05-30 | — | — | EP | claimed |
| WO-2000008046-A1 | MONOCYCLIC COMPOUNDS HAVING NK-2 ANTAGONIST ACTION AND COMPOSITIONS CONTAINING THEM | MENARINI RICERCHE S.P.A. (IT) | 2000-02-17 | — | — | WO | claimed |
| EP-0854139-B1 | Vitamin D3 derivative and production process thereof | TEIJIN LTD (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-1102789-A1 | MONOCYCLIC COMPOUNDS HAVING NK-2 ANTAGONIST ACTION AND COMPOSITIONS CONTAINING THEM | Menarini Ricerche S.p.A. (IT) | 2001-05-30 | — | — | EP | disclosed |
| EP-0854138-B1 | Vitamin D3 derivative and production process thereof | TEIJIN LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-6177586-B1 | USEFUL AS A PHARMACEUTICAL SUCH AS AN AGENT FOR PROMOTING BONE FORMATION, AN AGENT FOR SUPPRESSING PROLIFERATION OF TUMOR CELLS, AN AGENT FOR HIGH CALCIUM BLOOD DISEASES, AND AN IMMUNOSUPPRESSION AGENT | TEIJIN LIMITED (JP) | 2001-01-23 | — | — | US | disclosed |
| WO-2000008046-A1 | MONOCYCLIC COMPOUNDS HAVING NK-2 ANTAGONIST ACTION AND COMPOSITIONS CONTAINING THEM | MENARINI RICERCHE S.P.A. (IT) | 2000-02-17 | — | — | WO | disclosed |
| US-5986112-A | STEROID DERIVATIVES AS ANTITUMOR AGENTS AND BLOOD METAL CONCENTRATES | TEIJIN LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0854138-A2 | Vitamin D3 derivative and production process thereof | TEIJIN LIMITED (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0854139-A2 | Vitamin D3 derivative and production process thereof | TEIJIN LIMITED (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0712843-A1 | VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1996-05-22 | — | — | EP | disclosed |