Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 4/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.39 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.33 |
| ▸ | IGF1R | P08069 | 2/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | POLA1 | P09884 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764785 | 1.00 | CDC25A (0.39) | CDC25ACDC25BUGT2B7IGF1RMET | |
| SCHEMBL7764782 | 1.00 | CDC25A (0.39) | CDC25ACDC25BUGT2B7IGF1RMET | |
| SCHEMBL8755387 | 0.89 | CDC25A (0.39) | CDC25ACDC25BUGT2B7IGF1RMET | |
| SCHEMBL7764308 | 0.82 | CDC25A (0.38) | CDC25ACDC25BBACE1 | |
| SCHEMBL7764298 | 0.82 | CDC25A (0.38) | CDC25ACDC25BBACE1 | |
| SCHEMBL7764301 | 0.82 | CDC25A (0.38) | CDC25ACDC25BBACE1 | |
| SCHEMBL7764768 | 0.81 | CDC25A (0.40) | CDC25ACDC25BBACE1 | |
| SCHEMBL7778969 | 0.81 | CDC25A (0.48) | CDC25ACDC25B | |
| SCHEMBL7776389 | 0.81 | CDC25A (0.48) | CDC25ACDC25B | |
| SCHEMBL7765817 | 0.81 | CDC25A (0.40) | CDC25ACDC25BBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854139-B1 | Vitamin D3 derivative and production process thereof | TEIJIN LTD (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0854138-B1 | Vitamin D3 derivative and production process thereof | TEIJIN LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-6177586-B1 | USEFUL AS A PHARMACEUTICAL SUCH AS AN AGENT FOR PROMOTING BONE FORMATION, AN AGENT FOR SUPPRESSING PROLIFERATION OF TUMOR CELLS, AN AGENT FOR HIGH CALCIUM BLOOD DISEASES, AND AN IMMUNOSUPPRESSION AGENT | TEIJIN LIMITED (JP) | 2001-01-23 | — | — | US | disclosed |
| US-5986112-A | STEROID DERIVATIVES AS ANTITUMOR AGENTS AND BLOOD METAL CONCENTRATES | TEIJIN LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0854139-A2 | Vitamin D3 derivative and production process thereof | TEIJIN LIMITED (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0854138-A2 | Vitamin D3 derivative and production process thereof | TEIJIN LIMITED (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5719297-A | Vitamin D3 derivatives and production process thereof | TEIJIN LIMITED (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0712843-A1 | VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1996-05-22 | — | — | EP | disclosed |