Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 18/20 | 0.86 |
| ▸ | ADAM17 | P78536 | 15/20 | 0.86 |
| ▸ | MMP13 | P45452 | 11/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242214 | 0.93 | MMP1 (1.00) | MMP1ADAM17MMP13 | |
| SCHEMBL6240627 | 0.92 | MMP1 (0.85) | MMP1ADAM17MMP13 | |
| SCHEMBL6236394 | 0.89 | MMP1 (0.80) | MMP1ADAM17MMP13 | |
| SCHEMBL6238751 | 0.89 | MMP1 (0.80) | MMP1ADAM17MMP13 | |
| SCHEMBL5756389 | 0.83 | MMP1 (0.71) | MMP1ADAM17MMP13 | |
| SCHEMBL7105952 | 0.83 | MMP1 (0.71) | MMP1ADAM17MMP13 | |
| SCHEMBL6238225 | 0.83 | MMP1 (0.70) | MMP1ADAM17MMP13 | |
| SCHEMBL6237846 | 0.83 | MMP1 (0.70) | MMP1ADAM17MMP13 | |
| SCHEMBL6238384 | 0.83 | MMP1 (0.83) | MMP1ADAM17MMP13 | |
| SCHEMBL6261177 | 0.83 | MMP1 (0.70) | MMP1ADAM17MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104412-A1 | TACE INHIBITORS | Pfizer Products Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009492-A1 | TACE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2000-02-24 | — | — | WO | disclosed |