Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608390 | 1.00 | HCAR2 (0.44) | HCAR2ATMMAPTCACNA1BAPBA1 | |
| SCHEMBL7764838 | 0.93 | HCAR2 (0.56) | HCAR2ATMMAPTCACNA1BAPBA1 | |
| SCHEMBL45652 | 0.82 | — | — | |
| SCHEMBL4606403 | 0.80 | HCAR2 (0.41) | HCAR2ATMMAPTCACNA1BAPBA1 | |
| SCHEMBL27342684 | 0.78 | HCAR2 (0.48) | HCAR2ATMMAPTALDH1A1LMNA | |
| SCHEMBL14535450 | 0.78 | HCAR2 (0.48) | HCAR2ATMMAPTALDH1A1LMNA | |
| SCHEMBL28517770 | 0.77 | MAPT (0.41) | HCAR2ATMMAPTCACNA1BAPBA1 | |
| SCHEMBL10688847 | 0.77 | HCAR2 (0.43) | HCAR2ATMMAPTCACNA1BAPBA1 | |
| SCHEMBL868205 | 0.77 | HCAR2 (0.43) | HCAR2ATMMAPTCACNA1BAPBA1 | |
| SCHEMBL868206 | 0.75 | HCAR2 (0.57) | HCAR2ATMMAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865420-B1 | UNSATURATED ESTERS AND THEIR USE IN COATING COMPOSITIONS | PPG IND OHIO INC (US) | 2001-07-11 | — | — | EP | disclosed |