Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914240 | 0.89 | ADRB3 (0.62) | ADRB3ADRB1ADRB2PTGS1SLC6A2 | |
| SCHEMBL5483306 | 0.87 | ADRB3 (0.65) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5483300 | 0.87 | ADRB3 (0.65) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6914248 | 0.85 | ADRB3 (0.53) | ADRB3ADRB1ADRB2PTGS1SLC6A2 | |
| SCHEMBL6907204 | 0.83 | ADRB3 (0.63) | ADRB3ADRB1ADRB2PTGS1SLC6A2 | |
| SCHEMBL6914776 | 0.83 | ADRB3 (0.65) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6906589 | 0.82 | ADRB3 (0.52) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6911769 | 0.82 | ADRB3 (0.54) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7593273 | 0.79 | ADRB3 (0.80) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5485060 | 0.79 | ADRB3 (0.54) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001039948-A | 3,7-DISUBSTITUTED INDOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVE | DAINIPPON PHARMACEUT CO LTD | 2001-02-13 | — | — | JP | disclosed |