SCHEMBL5483300

SCHEMBL5483300

CCN(CC)C(=O)COc1cccc2c(C[C@@H](C)NC[C@H](O)c3ccc(O)cc3)c[nH]c12

nearest known ligand 0.65

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 20/20 0.65
ADRB1 P08588 11/20 0.65
ADRB2 P07550 11/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5483306 1.00 ADRB3 (0.65) ADRB3ADRB1ADRB2
SCHEMBL5482118 0.88 ADRB3 (0.76) ADRB3ADRB1ADRB2
SCHEMBL5482124 0.88 ADRB3 (0.76) ADRB3ADRB1ADRB2
SCHEMBL7593273 0.87 ADRB3 (0.80) ADRB3ADRB1ADRB2
SCHEMBL7765020 0.87 ADRB3 (0.55) ADRB3ADRB1ADRB2
SCHEMBL5484826 0.87 ADRB3 (0.64) ADRB3ADRB1ADRB2
SCHEMBL5484822 0.87 ADRB3 (0.64) ADRB3ADRB1ADRB2
SCHEMBL5484819 0.87 ADRB3 (0.64) ADRB3ADRB1ADRB2
SCHEMBL5476730 0.85 ADRB3 (0.68) ADRB3ADRB1ADRB2
SCHEMBL5476759 0.85 ADRB3 (0.68) ADRB3ADRB1ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7217724-B2 Indole, indazole, and benzazole derivative DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2007-05-15 US disclosed
US-20060063762-A1 Indole indazole and benzazole derivative DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2006-03-23 US disclosed
EP-1514869-A1 INDOLE, INDAZOLE, AND BENZAZOLE DERIVATIVE SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2005-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063762-A1 Indole indazole and benzazole derivative ADRB3, ADRA2C, ADRB2 ADRB3 1/4885ADRB1 4/4885ADRB2 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.