⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782213 | 0.78 | — | — | |
| SCHEMBL2221546 | 0.78 | — | — | |
| SCHEMBL1229565 | 0.78 | — | — | |
| SCHEMBL1045848 | 0.78 | — | — | |
| SCHEMBL9397842 | 0.76 | TTR (0.33) | — | |
| SCHEMBL12522817 | 0.67 | TTR (0.43) | — | |
| SCHEMBL16952063 | 0.67 | TTR (0.43) | — | |
| SCHEMBL7765122 | 0.67 | — | — | |
| SCHEMBL16956410 | 0.67 | — | — | |
| SCHEMBL4016732 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279655-A | Pharmaceutical use of cyclic peptide compounds | 中外制药株式会社 | 2023-12-22 | — | — | CN | disclosed |
| CN-1090621-C | Process for preparing quinazolin-4-one derivatives | OTSUKA PHARMA CO LTD (JP) | 2002-09-11 | — | — | CN | disclosed |
| EP-0749974-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2001-06-27 | — | — | EP | disclosed |
| CN-1066739-C | Phosphonic diester deriv | OTSUKA PHARMA CO LTD (JP) | 2001-06-06 | — | — | CN | disclosed |
| US-5922866-A | REACTING A TRIALKYLSILYL HALIDE WITH A 1,2-AMIDE SUBSTITUTED BENZENE DERIVATIVE IN THE PRESENCE OF A BASE; USE AS PHARMACEUTICALS OR INTERMEDIATES FOR SYNTHESIS THEREOF, SUCH AS ANTIDIABETIC DRUGS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-07-13 | — | — | US | disclosed |
| CN-1193967-A | Process for producing quinazoline-4-one derivatives | OTSUKA PHARMA CO LTD (US) | 1998-09-23 | — | — | CN | disclosed |
| US-5798344-A | TREATING DIABETES, HYPERLIPIDEMIA | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-08-25 | — | — | US | disclosed |
| CN-1147257-A | Phosphonic diester deriv | OTSUKA PHARMA CO LTD (JP) | 1997-04-09 | — | — | CN | disclosed |
| EP-0749974-A1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-12-27 | — | — | EP | disclosed |