SCHEMBL7765154

SCHEMBL7765154

CCCCC[Si@H]1CC[C@H]([C@H]2CC[C@H](CCCCc3cc(F)c(OCCF)c(F)c3)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 3/20 0.33
ITGA2B P08514 3/20 0.33
CNR1 P21554 3/20 0.32
CNR2 P34972 3/20 0.32
FFAR4 Q5NUL3 1/20 0.30
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7765162 1.00 ITGB3 (0.33) ITGB3ITGA2BCNR1CNR2FFAR4
SCHEMBL7765149 1.00 ITGB3 (0.33) ITGB3ITGA2BCNR1CNR2FFAR4
SCHEMBL7766069 0.92 ITGB3 (0.31) ITGB3ITGA2BCNR1CNR2THRA
SCHEMBL7766079 0.92 ITGB3 (0.31) ITGB3ITGA2BCNR1CNR2THRA
SCHEMBL7766076 0.92 ITGB3 (0.31) ITGB3ITGA2BCNR1CNR2THRA
SCHEMBL7765344 0.90 ITGB3 (0.32) ITGB3ITGA2B
SCHEMBL7765349 0.90 ITGB3 (0.32) ITGB3ITGA2B
SCHEMBL7765337 0.90 ITGB3 (0.32) ITGB3ITGA2B
SCHEMBL7767697 0.88 ITGB3 (0.31) ITGB3ITGA2B
SCHEMBL7767698 0.88 ITGB3 (0.31) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727428-B1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHINETSU CHEMICAL CO (JP) 2001-06-06 EP disclosed
US-5665271-A Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-09-09 US disclosed
EP-0727428-A1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-08-21 EP disclosed