SCHEMBL7765336

SCHEMBL7765336

Cc1ccc(-c2cc(-c3ccc(Nc4ccccc4)cc3)ccc2Nc2ccccc2)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.47
NPSR1 Q6W5P4 1/20 0.44
GAA P10253 5/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 1/20 0.40
CXCR2 P25025 2/20 0.39
PTGER4 P35408 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38
MAPT P10636 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 2/20 0.37
ALOX12 P18054 2/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
PTGS1 P23219 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3455261 0.87 HPGD (0.43) HPGDNPSR1GAAPTGER4MEN1
SCHEMBL10397632 0.82 GAA (0.44) HPGDNPSR1GAANPC1RAB9A
SCHEMBL10336976 0.82 HPGD (0.46) HPGDNPSR1GAANPC1RAB9A
SCHEMBL1931336 0.81 NPSR1 (0.53) HPGDNPSR1GAAPTGER4MEN1
SCHEMBL7765343 0.81 HPGD (0.52) HPGDNPSR1GAAMEN1KMT2A
SCHEMBL30477867 0.80 MAPT (0.52) HPGDNPSR1GAANPC1RAB9A
SCHEMBL12388896 0.80 MAPT (0.52) HPGDNPSR1GAANPC1RAB9A
SCHEMBL13580077 0.80 MAPT (0.52) HPGDNPSR1GAANPC1RAB9A
SCHEMBL10019438 0.80 MAPT (0.52) HPGDNPSR1GAANPC1RAB9A
SCHEMBL1004212 0.79 MAPT (0.49) HPGDNPSR1GAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707245-B1 Electrophotographic method KYOCERA MITA CORP (JP) 2001-06-20 EP disclosed
EP-0707245-A2 Electrophotographic method MITA INDUSTRIAL CO., LTD. (JP) 1996-04-17 EP disclosed