SCHEMBL7765343

SCHEMBL7765343

Cc1ccc(-c2cc(Nc3ccccc3)ccc2-c2ccc(Nc3ccccc3)cc2)c(C)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.52
NPSR1 Q6W5P4 1/20 0.51
APP P05067 2/20 0.45
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
ALDH1A1 P00352 5/20 0.41
MAPT P10636 2/20 0.41
AR P10275 1/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
HSD17B10 Q99714 3/20 0.41
ALOX12 P18054 2/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
MAPK1 P28482 1/20 0.41
PTGS2 P35354 1/20 0.41
HTR2B P41595 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23581982 0.87 APP (0.47) HPGDNPSR1APPMEN1KMT2A
SCHEMBL5667088 0.85 APP (0.44) HPGDNPSR1APPMEN1KMT2A
SCHEMBL18389550 0.84 HPGD (0.60) HPGDNPSR1APPMEN1KMT2A
SCHEMBL18173610 0.83 HPGD (0.64) HPGDNPSR1APPMEN1KMT2A
SCHEMBL3718540 0.83 HPGD (0.59) HPGDNPSR1APPMEN1KMT2A
SCHEMBL30161167 0.83 NPSR1 (0.68) HPGDNPSR1APPMEN1KMT2A
SCHEMBL29936559 0.81 NPSR1 (0.61) HPGDNPSR1APPMEN1KMT2A
SCHEMBL1931335 0.81 NPSR1 (0.61) HPGDNPSR1APPMEN1KMT2A
SCHEMBL13308526 0.81 HPGD (0.58) HPGDNPSR1APPMEN1KMT2A
SCHEMBL4639004 0.81 HPGD (0.58) HPGDNPSR1APPMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707245-B1 Electrophotographic method KYOCERA MITA CORP (JP) 2001-06-20 EP disclosed
EP-0707245-A2 Electrophotographic method MITA INDUSTRIAL CO., LTD. (JP) 1996-04-17 EP disclosed