Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601572 | 0.82 | TSHR (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20214256 | 0.79 | TSHR (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16295375 | 0.79 | TSHR (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10044323 | 0.79 | TSHR (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6886176 | 0.79 | THRB (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19683949 | 0.79 | HDAC3 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19678496 | 0.79 | HDAC3 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL21911763 | 0.78 | HDAC3 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19678503 | 0.77 | HDAC3 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL26586766 | 0.76 | HDAC3 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685454-B2 | X-ray opaque dental materials | IVOCLAR VIVADENT AG (LI) | 2001-06-27 | — | — | EP | disclosed |
| US-5780668-A | A CURABLE MONOMER OF A (MONO-, DI- OR TRIACRYLOYLOXY-SUBSTITUTED ALKYLENEAMIDO OR OXYCARBONYL-) -TRIODOBENZENES; REPLACES FILLERS IN CROWNS, BRIDGES ETC.; UV RESISTANCE; STABILITY | IVOCLAR AG (LI) | 1998-07-14 | — | — | US | disclosed |
| EP-0685454-B1 | X-ray opaque dental materials | IVOCLAR AG (LI) | 1997-10-15 | — | — | EP | disclosed |
| EP-0685454-A1 | X-ray opaque dental materials | IVOCLAR AG (LI) | 1995-12-06 | — | — | EP | disclosed |