SCHEMBL7765397

SCHEMBL7765397

CC1(C)CC(OCC2CO2)CC(C)(C)N1OC1CCCCC1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 2/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL892882 0.80 TSHR (0.35) TSHRMAPK1SMN1; SMN2
SCHEMBL13460519 0.77 NPC1 (0.36)
SCHEMBL893030 0.77 TSHR (0.33) TSHRMAPK1SMN1; SMN2
SCHEMBL355765 0.76 TSHR (0.37) TP53TSHRMAPK1SMN1; SMN2
SCHEMBL3237384 0.75 TSHR (0.44) TP53CYP3A4TSHRMAPK1SMN1; SMN2
SCHEMBL472962 0.75 TSHR (0.44) TP53CYP3A4TSHRMAPK1SMN1; SMN2
SCHEMBL28660114 0.75 TSHR (0.44) TP53CYP3A4TSHRMAPK1SMN1; SMN2
SCHEMBL19838618 0.75 TSHR (0.44) TP53CYP3A4TSHRMAPK1SMN1; SMN2
SCHEMBL9040363 0.75 KDM4E (0.39) SMN1; SMN2
SCHEMBL7935333 0.75 EPHX2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0745646-B1 Antioxidants and light stabilizers on carriers as fillers and stabilizers CIBA SC HOLDING AG (CH) 2001-07-18 EP disclosed
EP-0634449-B1 Polyether with sterically hindered amine side chains as stabilizing agents CIBA GEIGY AG (CH) 1999-09-01 EP disclosed
US-5892037-A Polymeric adducts of hindered amine-epoxides as stabilizers CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-04-06 US disclosed
US-5719257-A OBTAINED BY ANIONIC POLYMERIZATION OF DERIVATIVES OF 2,2,6,6-TETRAMETHYL-4-/2,3-EPOXYPROPOXY/PIPERIDINE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-02-17 US disclosed
US-5665885-A FOR STABILIZING ORGANIC MATERIAL AGAINST THE DAMAGING INFLUENCE OF LIGHT, OXYGEN AND/OR HEAT CIBA-GEIGY CORPORATION (US) 1997-09-09 US disclosed
US-5637714-A OXIDATION AND HEAT RESISTANCE; PHOTOSTABILITY CIBA-GEIGY CORPORATION (US) 1997-06-10 US disclosed
US-5616637-A PHOTOSTABILITY; OXIDTION AND HEAT RESISTANT CIBA-GEIGY CORPORATION (US) 1997-04-01 US disclosed
EP-0745646-A1 Antioxidants and light stabilizers on carriers as fillers and stabilizers CIBA-GEIGY AG (CH) 1996-12-04 EP disclosed
US-5574162-A CONTAIN REACTIVE FUNCTIONAL GROUP, I.E., HYDROXY, AMINO, ISOCYANATO, GLYCIDYLOXY, TRIHYDROXYSILYL OR TRIALKOXYSILYL, WHICH CAN BE CHEMICALLY ATTACHED TO POLYMER SUBSTRATES CIBA-GEIGY CORPORATION (US) 1996-11-12 US disclosed
US-5541274-A Polymeric adducts of hindered amine-epoxides as stabilizers CIBA-GEIGY CORPORATION (US) 1996-07-30 US disclosed
US-5457204-A For polymers CIBA-GEIGY CORPORATION (US) 1995-10-10 US disclosed
US-5442071-A Photostability CIBA-GEIGY CORPORATION (US) 1995-08-15 US disclosed
EP-0638597-A1 Polymeric adults of hindered amine-epoxydes as stabilizers CIBA-GEIGY AG (CH) 1995-02-15 EP disclosed
EP-0634399-A1 Adducts of hindered amine-epoxides as stabilisers CIBA-GEIGY AG (CH) 1995-01-18 EP disclosed
EP-0634449-A2 Polyether with sterically hindered amine side chains as stabilizing agents CIBA-GEIGY AG (CH) 1995-01-18 EP disclosed
US-5359069-A Non-migrating 1-hydrocarbyloxy hindered amine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-10-25 US disclosed
US-5286865-A Contain reactive functional group which can be chemically attached to selected polymer substrates CIBA-GEIGY CORPORATION (US) 1994-02-15 US disclosed
US-5145893-A Photostability CIBA-GEIGY CORPORATION (US) 1992-09-08 US disclosed
EP-0389419-A1 Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed
EP-0365481-A1 Polymeric substrates stabilized with N-substituted hindered amines CIBA-GEIGY AG (CH) 1990-04-25 EP disclosed