Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892882 | 0.83 | TSHR (0.35) | TSHRMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7769311 | 0.83 | ALDH1A1 (0.49) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL25452965 | 0.80 | TSHR (0.35) | TSHRMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL355765 | 0.80 | TSHR (0.37) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL2171107 | 0.78 | TSHR (0.36) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL2142862 | 0.78 | TSHR (0.36) | TSHRMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL7765397 | 0.77 | TP53 (0.31) | TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL11009382 | 0.77 | TSHR (0.35) | TSHRMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10897968 | 0.74 | TSHR (0.33) | TSHRMAPK1ALDH1A1 | |
| SCHEMBL18878973 | 0.73 | ALDH1A1 (0.30) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440524-A1 | STERICALLY HINDERED AMINE STABILIZERS | BASF SE (DE) | 2012-04-18 | — | — | EP | disclosed |
| US-20120083557-A1 | STERICALLY HINDERED AMINE STABILIZERS | BASF SE (DE) | 2012-04-05 | — | — | US | disclosed |
| WO-2010142572-A1 | STERICALLY HINDERED AMINE STABILIZERS | BASF SE (DE) | 2010-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083557-A1 | STERICALLY HINDERED AMINE STABILIZERS | AAAS, H1-5, H1-2 | TSHR 3145/4885MAPK1 3016/4885SMN1; SMN2 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.